摘要
目的探讨磁敏感加权成像(SWI)对脑梗死的诊断价值。材料与方法30例患者在3.0 T MR成像系统行常规MRI、扩散加权成像(DWI)和SWI,20例同时行MR血管成像(MRA),19例行静脉注射Gd-DTPA增强扫描。将SWI采集的原始数据传输到GE AW4.4工作站离线处理,得到校正相位图(CPI)和磁化率加权图。手动测量脑梗死区及水肿区与正常对照区的CP值,采用t检验进行比较,以P<0.05为差异有统计学意义。结果 30例脑梗死在DWI上表现为高信号,15例MRA图像可见大脑前、中、后动脉不同程度的狭窄或闭塞。5例SWI上可见大脑中动脉内血栓,与MRA图像显示的区域相一致;21例SWI上病灶内合并出血,CT发现9例,T1WI仅发现2例;SWI显示15例梗死区静脉血管增多,6例静脉血管分布正常,9例静脉血管分布减少。梗死区与正常对照区的CP值分别为-0.021±0.006、-0.006±0.005,差异有统计学意义(t=-2.359,P<0.05);水肿区与正常对照区的CP值分别为-4.853±0.005、-1.868±0.003,差异有统计学意义(t=-2.172,P<0.05)。结论 SWI对脑梗死急性期并发的出血及静脉血管分布的显示具有常规MRI无可替代的优势,对脑梗死急性期治疗具有重要的指导作用;并且校正相位图可以进行定量分析。
Objectives： To explore the diagnosis value of susceptibility-weighted imaging（SWI） in cerebral ischemic stroke. Materials and Methods： Thirty cases with acute infarction were imaged with conventional MRI,DWI and SWI. Twenty of thirty cases were examined with MRA 19 cases were examined with postcontrast MRI after injection of Gd-DTPA. The raw data of SWI were transferred to the advantage workstations AW 4.4 which were generated the corrected phase image（CPI） and the minimum intensity projection. The corrected phase（CP） values were obtained manually at the infarction or edema and control regions. Results： Thirty cases with acute infarction were shown hyper-intensity on DWI. 15 cases were shown stenosis or occlusion of anterior cerebral artery middle cerebral artery（MCA） and posterior cerebral artery on MRA. Five cases showed right MCA clots consisted with the broken region of MRA on SWI. SWI showed hemorrhage of 21 in 30 cases（while CT,n=9. Only T1 WI,n=2）. 24 cases showed abnormal cerebral veins distribution in infarction area（increased in 15 cases,decreased in 9 cases）. The average CP values of the infarction and the control area were-0.021±0.006 and-0.006±0.005,respectively（t =2.167,P〈0.05）. The average CP values of the edema and the control area were-4.853±0.005 and-1.868±0.003,respectively（t =-2.172,P〈0.05）. Conclusions： SWI has more predominant advantages than conventional MRI in detecting cerebral infarction accompanying hemorrhage and vein structure. And the corrected phase image（CPI） can be quantitatively analyzed.
出处
《磁共振成像》
CAS
CSCD
2015年第3期182-186,共5页
Chinese Journal of Magnetic Resonance Imaging
关键词
脑梗死
磁共振成像
Cerebral ischemic stroke
Magnetic resonance imaging
