摘要
目的:优化荷叶中槲皮素提取工艺条件。方法:在单因素试验的基础上,以槲皮素提取量为响应值,选择盐酸体积分数、加热温度和加热时间为因素,采用Box-Behnken响应面法设计优化提取工艺。结果:最优提取工艺为11.0%盐酸、加热时间120min、加热温度79.0。在此工艺下荷叶中槲皮素提取量为12.049 6 mg/g,接近预测值11.794 2 mg/g。结论:优化工艺稳定、可行,可为进一步开发应用荷叶槲皮素提供科学依据。
OBJECTIVE：To optimize the extraction process of quercetin from Folium nelumbinis. METHODS：Based on single-factor experiment,with the extraction amount of quercetin as the response value,and the volume fraction of hydrochloric acid,heating temperature and heating time as the factors,Box-Behnken response surface design was adopted to optimize the extraction process. RESULTS：The optimal extraction process was as follows as the volume fraction of hydrochloric acid of 11.0%,heating time of 120 min,and heating temperature of 79.0. By the above process,the extraction amount of quercetin from Folium nelumbinis was 12.049 6 mg/g,close to the predicted value of 11.794 2 mg/g. CONCLUSIONS：The optimized process is stable and feasible,and can provide a scientific basis for further application of quercetin from Folium nelumbinis.
出处
《中国药房》
CAS
北大核心
2015年第10期1397-1400,共4页
China Pharmacy
关键词
荷叶
槲皮素
提取工艺
盐酸水解
响应面法
优化
Folium nelumbinis
Quercetin
Extraction process
Hydrochloric acid hydrolysis
Response surface method
Opti-mization
