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循环miRNA检测方法研究进展及其临床应用 被引量:5

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摘要 microRNA(miRNA)是一种保守的、非编码的小RNA,长度约为22个核苷酸。首次发现于Caenorhabditisy线虫体内,现有的技术已发现1000多种microRNA。miRNA存在于低级生物、植物、高等动物等多种生物中,在正常与疾病状态下,参与调节免疫、细胞周期、生物代谢和凋亡等多个生物过程。
出处 《中华实验和临床感染病杂志(电子版)》 CAS 2015年第1期108-112,共5页 Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Edition)
基金 首都医学科学发展基金(No.2007-3054) 国家自然科学基金(No.81201160) 国家科技重大专项课题(No.2014ZX10005001)
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