摘要
目的:对皮下修剪术与皮下抽吸术两种手术方法治疗腋臭的临床疗效进行系统评价。方法:应用计算机检索相关文献数据库,收集国内外报道有关皮下修剪、抽吸两种手术方法治疗腋臭的临床随机对照试验,评价纳入研究的方法学质量并进行资料提取后,采用Rev Man 5.0软件进行Meta分析。结果:最终共纳入7个中文随机对照研究,共557个研究对象,修剪组292(47侧+245例),抽吸组265(50侧+215例),Meta分析结果显示皮下修剪术治愈率(OR=4.32,P=0.02)、总有效率(OR=3.76,P<0.0001)较抽吸术高,复发率比抽吸术低(OR=0.23,P=0.0009);而皮下抽吸术并发症较修剪术低(OR=6.65,P<0.00001);手术时间及出血量抽吸术均较修剪术少(P<0.05)。结论:现有数据Meta分析结果表明皮下修剪术较皮下抽吸术治疗腋臭具有治愈率、复发率低优势,而皮下抽吸术较皮下修剪术有其并发症低、手术时间短、术中出血少的优点。由于文献质量普遍不高,纳入样本量偏少,今后,尚需进一步开展设计良好、方法学质量更高的临床随机对照试验。
Objective To systemically analyze the different clinical efficacy of axillary osmidrosis between subcutaneous pruning and liposuction. Methods The relevant database were searched to collect all the randomized controlled trials（RCT） that compared the domestic different clinical efficacy of axillary osmidrosis between subcutaneous pruning and subcutaneous liposuction according to the principles of systematic review. The quality of the included studies was evaluated and Meta-analysis were performed using Rev Man5.0 software. Results Seven RCT which included 557 patients were enrolled in our study. Two hundren and ninety two cases（47 axillae and 245 patients）were included in subcutaneous pruning group,while 265 cases（50 axillae and 215 patients） were included in subcutaneous liposuction group.The results of the Meta-analysis indicated that the curative rate（OR=4.32,P=0.02）and the total effective rate（OR=3.76,P0.0001）of subcutaneous pruning were superior to the subcutaneous liposuction. The recurrence rate of subcutaneous liposuction was superior to the subcutaneous pruning（OR=0.23,P=0.0009）. However, smaller complication rate（OR=6.65,P0.00001）,shorter operation time（P0.05） and less blood loss（P0.05） were observed in subcutaneous liposuction group while compared with subcutaneous pruning group. Conclusions According to the results of the Meta-analysis, the subcutaneous pruning treatment for axillary osmidrosis was associated with improved outcomes in terms of greater curative, effective rate and smaller recurrence rate. However,shorter operation time,less blood loss, smaller complication rate could be considered as the advantages of subcutaneous liposuction.Due to median quality and small size of the included studies,further well-designed RCT should be performed.
出处
《中国美容医学》
CAS
2015年第4期7-12,共6页
Chinese Journal of Aesthetic Medicine
关键词
腋臭
皮下修剪术
皮下抽吸术
临床随机对照试验
META分析
axillary osmidrosis
subcutaneous pruning
subcutaneous liposuction
randomized controlled trials
Meta-analysis
