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不同剂量右美托咪定对腹部手术患者血糖浓度和心率的影响 被引量:13

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摘要 目的:探讨不同剂量的右美托咪定对腹部手术患者血糖浓度和心率的影响,为临床麻醉合理用药提供依据。方法选取该院2013年1~9月择期腹部手术行全身麻醉患者80例,分为生理盐水对照组(S组)、右美托咪定0.6μg/kg剂量组(D1组)、0.8μg/kg剂量组(D2组)和1μg/kg剂量组(D3组),每组各20例。检测患者插管后30 min、手术后1 h和手术后6 h的血糖浓度;监测并记录患者麻醉诱导前、麻醉诱导后、插管后、手术15、30、45、60、75、90、105、120 min和术后15 min的心率变化。结果手术后1 h ,D2组和D3组患者血糖浓度显著低于S组(P<0.05),插管后30 min和手术后6 h ,各组比较差异均无统计学意义(P>0.05)。与S组患者同一时间的心率比较,D2组患者在插管后60、75、90 min心率显著降低(P<0.05),D3组在整个手术期间均显著性降低(P<0.05)。结论右美托咪定能够缓解患者围术期应激反应的血糖浓度和心率变化。
作者 袁鹏
出处 《重庆医学》 CAS 北大核心 2015年第9期1263-1265,共3页 Chongqing medicine
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参考文献10

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