摘要
目的探讨一种能有效、安全地降低疼痛,小儿易于接受的口腔护理方法。方法选取2011年1月~2014年7月在广州医科大学第一附属医院,应用大剂量甲氨蝶呤化疗后合并Ⅱ度及以上口腔黏膜炎的白血病患儿128例,随机分为观察组和对照组,对照组采用传统口腔擦洗方法,观察组采用输液式口腔冲洗方法,观察两组患儿口腔黏膜炎愈合情况、口腔护理过程中的疼痛程度、依从性、家长满意度。结果观察组患儿口腔黏膜炎愈合效果总有效率[87.5%（56/64）]高于对照组[62.5%（40/64）],差异有高度统计学意义（P〈0.01）;观察组患儿的疼痛评分[（2.38±0.41）分]低于对照组[（4.05±0.67）分],差异有高度统计学意义（P〈0.01）。观察组患儿依从率[81.3%（52/64）]显著高于对照组[34.4%（22/64）],家长满意率[87.5%（56/64）]显著高于对照组[21.9%（14/64）],差异均有高度统计学意义（P〈0.01）。结论输液式口腔冲洗方法应用在化疗后发生口腔黏膜炎的白血病患儿中整体效果好,是值得临床推广的一种口腔护理方法。
Objective To explore an acceptable method of oral care which reduces pain effectively and safely. Methods From January 2011 to July 2014, in the First Affiliated Hospital of Guangzhou Medical University, 128 children with leukemia occurred oral mucositis after high dose Methotrexate（MTX） were divided in two groups randomly, observation group with oral rinse and control group with traditional oral care, the healing effect of oral mucositis, pain degree, nursing adherence and children＇s family member satisfaction during the process of oral care of two groups were observed.Results The total effective rate of oral mucositis in observation group [87.5%,（56/64）] was higher than that in control group [62.5%,（40/64）], the difference was statistically significant（P〈0.01）; the pain score in observation group [（2.38±0.41） scores] was lower than that in control group [（4.05±0.67） scores], the difference was statistically significant（P〈0.01）.Nursing adherence rate and children＇s family member satisfaction rate in observation group [81.3%（52/64）, 87.5%（56/64）] were higher than those in control group [34.4%（22/64）, 21.9%（14/64）], the difference was statistically significant（P〈0.01）. Conclusion Oral rinse is good for oral mucositis on children with leukemia after high dose MTX chemotherapy treatment, and it is worth of spreading in clinical.
出处
《中国医药导报》
CAS
2015年第7期55-57,共3页
China Medical Herald
基金
广东省医学科研基金立项课题(编号A2014298)
