摘要
目的探讨抗CCP、RF和CRP联合检测诊断类风湿关节炎的临床价值。方法选取本院2012年4月-2014年7月收治的82例类风湿性关节炎患者作为实验组,选择同期收治的79例自身免疫性疾病患者作为对照组。抽取静脉晨血检测RF、抗CCP和CRP,分析其临床价值。结果实验组抗CCP、CRP、RF及联合检测阳性率均高于对照组,差异有统计学意义（P〈0.05）。联合检测抗CCP、CRP、RF的灵敏度（53.67%）最低,特异度（97.32%）最高,与抗CCP、RF和CRP检测比较差异均有统计学意义（P〈0.05）。结论抗CCP、CRP及RF在类风湿关节炎中表达阳性率较高,联合检测抗CCP、CRP、RF可显著提高检测特异度。
Objective To discuss clinical value on combination detection of anti-CCP,RF and CRP in the diagnosis of rheumatoid arthritis. Methods 82 patients with rheumatoid arthritis admitted in our hospital from April 2012 to July2014 were selected as experimental group,and 79 patients with autoimmune diseases over the same period were selected as control group.The level of RF,anti-CCP and CRP were tested through extractting the morning venous blood,its clinical value was analyzed. Results The positive rate of the anti-CCP,CRP,RF and combination detection in experimental group was higher than that in control group respectively,with statistical difference（P0.05）.The sensitivity on the combination detection of serum anti-CCP,RF,CRP was the lowest（53.67%）,but the specificity was highest（97.32%）,compared with anti-CCP,RF and CRP detection,with statistical difference（P0.05）. Conclusion The expression positive rate of serum anti-CCP,RF,CRP in rheumatoid arthritis are higher,the combination detection of serum anti-CCP,RF,CRP can significantly improve the detection specificity.
出处
《中国当代医药》
2015年第9期134-135,138,共3页
China Modern Medicine
