摘要
目的探讨宫腔填纱配合米索前列醇局部给药治疗剖宫产产后出血的疗效。方法选取2012年1月至2013年6月妇产科收治的孕产妇140例,均行剖宫产手术且均因收缩乏力而引起产后出血。采用随机数字表法分观察组和对照组,各70例。对照组采用常规法治疗,观察组采用宫腔填纱配合米索前列醇局部给药治疗。结果观察组产妇治疗有效率为98.57%,明显高于对照组的80.00%(χ2=12.619,P<0.05);观察组治疗后产褥感染率和子宫切除率均为1.43%,明显低于对照组的11.43%和10.00%(χ2=5.444和4.500,均P<0.05);观察组手术时间和出血量分别为(58.62±6.74)min和(520.45±218.50)mL,显著低于对照组的(88.41±7.10)min和(950.23±410.56)mL(t=17.52,7.74,均P<0.05);观察组治疗过程中不良反应发生率为1.43%,显著低于对照组的10.00%(χ2=4.500,P<0.05)。结论宫腔填纱配合米索前列醇局部给药治疗剖宫产产后出血疗效好、操作简单、经济可行、不良反应少,对于减少产后出血、降低孕产妇产褥感染率和避免子宫切除具有重要作用,值得推广。
Objective To observe the efficacy of intrauterine packing gauze coordinated with topical application of misoprostol for treating postpartum hemorrhage.Methods 140 parturients with cesarean section in the gynecology and obstetrics department of our hospital from January 2012 to June 2013 were selected and appeared postpartum hemorrhage due to uterine atony.All the parturients were randomly divided into the two groups according to the random number table method：observation group（n=70） and control group（n =70）.The con-trol group was treated by the conventional treatment method,while the observation group adopted the intrauterine packing gauze coordinated with topical application of misoprostol.The efficacies were observed and compared between the two kinds of method. Results The effective rate of the observation group was 98.57%,while the rate of control group was 80.00%,the observation group was signifi-cantly higher than the control group（χ2=12.619,P〈0.05）;the observation group had 1 case of puerperal infection after treatment and 1 case of hysterectomy（1.43%）,while the control group had 8 cases（11.43%） of puerperal infection and 7 cases（10.00%） of hys-terectomy,the puerperal infection rate and hysterectomy rate in the observation group were significantly lower than those in the control group（χ^2=5.444,4.500,P〈0.05）;the operative time and bleeding volume in the observation group were（58.62±6.74）min and（520.45 ±218.50）m L respectively,which were significantly lower than（88.41 ±7.10）min and（950.23 ±410.56）m L in the control group respectively（t =17.52,7.74,P〈0.05）.The occurrence rate of adverse reactions in the observation group was 1.43%,which was significantly lower than 10.00% in the control group（χ^2=4.500,P〈0.05）. Conclusion Untrauterine packing gauze coordinated with topical application of misoprostol for treating postpartum hemorrhage after cesarean section has better effect,is simple to operate,economi-cal and feasible with less adverse reactions,which is a safe,rapid and effective hemostasis method,has an important role in reducing postpartum hemorrhage,decreasing puerperal infection in parturients and hysterectomy and deserves to be promoted and applied.
出处
《中国药业》
CAS
2015年第7期79-81,共3页
China Pharmaceuticals
关键词
剖宫产
产后出血
宫腔填纱
米索前列醇
疗效
cesarean section
postpartum hemorrhage
intrauterine packing gauze
misoprostol
curative efficacy
