摘要
目的分析总结肺结核患者医院感染的临床特征,分析易感因素,为降低肺结核患者医院感染的发生率,提出预防控制措施。方法回顾性分析2005年1月至2013年12月中山大学第五附属医院肺结核患者的资料,观察医院感染发生率、发生部位及病原学分布特点等。结果 1 304例肺结核患者中有79例发生医院感染,感染率6.06%,医院感染部位以下呼吸道最多见,占66.06%。103份送检标本中,共检出病原体89株,检出率为86.41%;其中革兰阴性菌29株(32.58%),革兰阳性菌9株(10.11%),真菌感染51例(57.30%)。单因素χ2检验结果显示,年龄≥60岁及使用其他抗生素是肺结核患者发生医院感染的危险因素(P<0.001)。结论肺结核患者医院感染主要发生于下呼吸道,病原菌以真菌为主,医院感染的发生与高龄、使用其他抗生素有关,需采取综合防治措施降低医院感染发生率。
Objective To investigate the clinical features of nosocomial infection in inpatients with pulmonary tuberculosis, analyze its susceptible factors, and put forward prevention and control measures to reduce the incidence of nosocomial infection of inpatients with pulmonary tuberculosis. Methods Retrospective survey was taken to analyze the data of patients with pulmonary tuberculosis from Jan 2005 to Dec 2013 for the infection rates, infection sites and pathogen inspection. Results Nosocomial infection occurred in 79 out of 1 304 patients, with the infection rate of 6.06%; among which the patients with lower respiratory tract infections accounted for 66.06%. Of total 103 specimens, 89 strains of pathogens were isolated, with the positive rate of 86.41%, including 29 （32.53%） strains of gram-negative bacteria, 9 （10.11%） strains of gram-positive bacteria, and 51 （57.3%） strains of fungi. Single factor X^2 test showed that age ≥60 years-old and use other antibiotic were the risk factors to nosocomial infection （P〈0.001）. Conclusion In inpatients with pulmonary tuberculosis, nosocomial infection occurred mainly in lower respiratory tract. Fungus is the common pathogen. Advanced age and use other antibiotic were related to nosocomial infection in inpatients with pulmonary tuberculosis. We should take comprehensive prevention and control measures to reduce the incidence of nosocomial infection.
出处
《热带医学杂志》
CAS
2015年第2期221-223,共3页
Journal of Tropical Medicine
关键词
肺结核
医院感染
调查分析
pulmonary tuberculosis
nosocomial infection
investigation and analysis
