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帕瑞昔布钠超前镇痛对乳腺癌改良根治术患者术后急性及慢性疼痛的影响 被引量:2

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摘要 目的研究帕瑞昔布钠超前镇痛对乳腺癌改良根治术患者术后急性及慢性疼痛的影响。方法40例择期行乳腺癌改良根治术患者,ASA分级I~Ⅱ级,随机分成A、B两组,每组20例,A组为帕瑞昔布钠组,在麻醉诱导前15 min静脉注射帕瑞昔布钠40 mg作为超前镇痛,B组为对照组静脉注射生理盐水5ml。术后两组患者均给予舒芬太尼PCIA。记录两组患者术后2 h、4 h、24 h和48 h疼痛视觉模拟评分(VAS),术后48 h内PCIA按压次数及术后慢性疼痛的发生情况。结果 A组在术后2 h、4 h、24 h和48 h VAS评分较B组低(P〈0.05)。A组术后48 h内PCIA按压次数明显低于B组(P〈0.05);两组患者术后慢性疼痛的发生情况差异无统计学意义(P〉0.05)。结论帕瑞昔布钠超前镇痛减少48 h内PCA自控按压次数,降低术后2 h、4 h、24 h和48 h VAS评分,对术后慢性疼痛的发生情况无影响。
出处 《新疆医学》 2015年第3期337-339,共3页 Xinjiang Medical Journal
基金 新疆医科大学创新基金项目(项目编号:XJC201489)
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参考文献9

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