摘要
目的：探讨沙培林在减少乳腺癌术后皮下积液中的应用，对比术中手术野喷洒和术后创腔保留灌洗两种临床疗效和安全性。方法收集乳腺癌患者66例，术前青霉素皮试阳性，不能用沙培林灌洗的患者19例作为观察组，余47例分为术中手术野喷洒组（25例）和术后灌洗组（22例）。观察手术日至拔管日时间。结果观察组平均置管时间为（17.37±5.67）d，术中喷洒组为（15.06±4.43）d，术后灌洗组为（11.72±3.51）d。观察组和术中喷洒组置管时间比较差异无统计学意义（ p〉0.05），术中喷洒组与术后灌洗组置管时间比较差异有统计学意义（ p〈0.05）。结论沙培林可以有效减少乳腺癌术后皮下积液的发生率。术后创腔灌洗是有效的方法。
Objective To investigate the use of Sapylin in reducing the subcutaneous hydrops in patients with breast cancer surgery,and to compare the effect and safety of two methods：spraying the oper-ative field during operation vs. lavaging the surgical residual cavity after operation. Methods Data of 66 patients with breast cancer from April 2013 to December 2013 in the same medical team were analyzed. A-mong them,19 patients who had a positive Penicillin skin test result were classified as control,and the oth-er 47 patients were randomly divided into two groups：22 in the spraying group and 25 in the lavaging group. The days from the operation to removing the drainage tube were recorded. Results In control group,the average indwelling time was 17. 37 ± 5. 67 d,in spraying group it was 15. 06 ± 4. 43 d,and in lavaging group it was 11. 72 ± 3. 51 d. There was no difference between control group and spraying group （p〉0. 05）,but there was significant difference between spraying group and lavaging group（p〈0. 05）. Conclusion Sapylin can reduce the occurrence of subcutaneous hydrops after breast operation. The post-operative lavage of surgical residual cavity may be a better way over spraying the operative field.
出处
《临床外科杂志》
2015年第3期198-199,共2页
Journal of Clinical Surgery
基金
华中科技大学自主创新研究基金(2014QN230)
关键词
沙培林
皮下积液
乳腺癌
Sapylin
subcutaneous hydrops
breast cancer
