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35例胃间质瘤临床诊疗分析 被引量:4

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摘要 目的:探讨胃间质瘤的临床表现、辅助检查特征、诊断及治疗方法。方法:回顾分析35例胃间质瘤患者的临床资料,统计和分析相关因素。结果:男女比例为1∶0.9,平均年龄(59.6±11.4)岁,肿瘤平均直径(4.5±4.4)cm;病理CD117阳性率91.40%,CD34阳性率88.60%;随访31例,中位存活时间(28.6±9.4)月。结论:胃间质瘤无特异性临床表现,超声内镜检查对诊断有重要的意义,确诊需要病理检查和免疫组化检查;CD117和CD34是胃间质瘤最重要的标记物;完整切除是首选治疗方式,靶向Z治疗药物伊马替尼可改善预后。
出处 《中国中西医结合外科杂志》 CAS 2015年第2期187-190,共4页 Chinese Journal of Surgery of Integrated Traditional and Western Medicine
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  • 1陈利,郭文.胃间质瘤的诊断和治疗进展[J].中国实用内科杂志,2006,26(2):232-234. 被引量:24
  • 2贺慧颖,方伟岗,钟镐镐,李燕,郑杰,杜娟,衡万杰,吴秉铨.165例胃肠道间质瘤中c-kit和PDGFRA基因突变的检测和临床诊断意义[J].中华病理学杂志,2006,35(5):262-266. 被引量:73
  • 3Aparicio T, Boige V, Sabourin JC, et al. Prognostic factors after surgery of p rimary respectable gastrointestinal stromal tumors [J]. Eur J Surg Oncol, 2004, 30(10): 1098-1103.
  • 4Lukaszezyk JJ, Preletz RJ. Laparoseop ic resection of benign stromal tumor of the stomach[J]. J Laparoendose Surg, 1992, 2(6):331-334.
  • 5Nguyen SQ?, Divino CM, Wang JL, et al. Laparoscopic management of gastrointestinal stromal tumors [J]. Surgical endoscopy, 2006, 20 (5): 713-716.
  • 6Hepworth CC, MenziesD, Motson RW Minimally invasive surgery for posterior gastric stromal tumors. Suvg Endosc, 2000, 14 : 349-353.
  • 7Moiz SR, Ganesan BH, Lee TD Laparoendoscopic removal of a benign gastric stromal tumor at the cardia. Journal of the Society of Laparoendoscopic Surgeons / Society of Laparoendoscopic Surgeons, 2006 Jan-Mar, 10: 117-121.
  • 8Novitsky YW, Kercher KW, Sing RF, et al. Long-term outcomes of laparoscopic resection of gastric gastrointestinal stromal tumors. Annals of surgery, 2006,243: 738-745.
  • 9Li J,Gong FJ,Shen L,et al.Post-operative imatinib in patients with intermediate or high risk gastrointestinal stromal tumour[J].Euro J Sur Oncol,2011,37(4):319-324.
  • 10Corless CL,Ballman KV,Antonescu C,et al.Relation of tumor pathologic and molecular features to outcome after surgical resection of localized primary gastrointestinal stromal tumor (GIST):Results of the intergroup phase Ⅲ trial ACOSOG Z9001[J].J Clin Oncol,2010,28 (15 Suppl):a10006.

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  • 1汪贤臣,施红,余秀华,张宏,李黎,徐爱芬,卫张蕊,孔梓祥,姚春,徐建平,郭心璋.胃间质瘤超声造影和胃镜检查应用比较[J].中华医学超声杂志(电子版),2011,8(5):1033-1038. 被引量:20
  • 2周志强,贺文俊.乙状结肠腺癌多发肝转移瘤钙化一例[J].中华临床医师杂志(电子版),2011,5(16):4921-4922. 被引量:1
  • 3Ginori Alessandro,Scaramuzzino Francesco,Marsili Stefania,Tripodi Sergio.Late Hepatic Metastasis From a Duodenal Gastrointestinal Stromal Tumor(29 Years After Surgery)[J].International Journal of Surgical Pathology,2015,234(4):123-141.
  • 4Jaclyn Frances Hechtman,Ahmet Zehir,Talia Mitchell,Laetitia Borsu,Samuel Singer,William Tap,Alifya Oultache,Marc Ladanyi,Khedoudja Nafa.Novel oncogene and tumor suppressor mutations in KIT and PDGFRA wild type gastrointestinal stromal tumors revealed by next generation sequencing[J].Genes Chromosomes Cancer,2015,43(7):314-319.
  • 5Senthil K.Selvanathan,Ramesh Kumar,John Goodden,Atul Tyagi,Paul Chumas.Evolving instrumentation for endoscopic tumour removal of CNS tumours[J].Acta Neurochirurgica,2013,15(5):451-455.
  • 6Aso A, Ihara E, Kubo H, et al. Gastric gastrointestinal stromal tumor smaller than 20 mm with liver metastasis[J]. Clin J Gas-troenterol,2013,6(1) :29.
  • 7Ulusan S, Koc Z, Kayaselcuk F. Imaging characteristics of liver metastasis from gastrointestinal stroma| tumor hefore and after imatinib mesylate treatment[J]. Turk J Gastroenterol, 2008, 19(2):129.
  • 8李建卫,吴松松,朱琳,沈仕华,陈圣.彩色多普勒超声鉴别诊断胃间质瘤与胃癌[J].中国医学影像技术,2011,27(6):1227-1230. 被引量:16
  • 9郎翠翠,李玉红,董新茜.超声内镜下胃间质瘤特征与病理诊断相关性研究[J].中华消化内镜杂志,2011,28(6):305-308. 被引量:20
  • 10刘青江,毛忠琦,周晓俊,李锐.胃间质瘤手术治疗151例体会[J].求医问药(下半月刊),2012,10(1):284-284. 被引量:3

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