摘要
目的:收集中药熏洗治疗膝关节骨性关节炎(KOA)的临床研究文献,分析其用药特点和规律。方法:检索近15年中药熏洗治疗KOA的临床文献,对药物及功效、性味及归经进行整理、归纳和分析。结果:有效文献共174篇,涉及221味中药;祛风湿药、活血化瘀药、补虚药的累计频率达到80.60%;药物应用频次以川乌、草乌、当归、红花、伸筋草为最高;四气中温、平、寒类药物的累计频率达到95.48%,五味中辛、苦、甘类药物的累计频率达94.12%;药物归经以肝、脾、肾为主。结论:中药熏洗治疗KOA以祛风湿药和活血化瘀药为主;治法以祛邪为主,主要从祛风除湿通络、活血化瘀、散寒止痛几方面论治,临床可根据证型灵活应用。
Objective： To collect clinical research literatures relevant to treatment of knee osteoarthritis（KOA）by Chinese medical fumigation to analyze its characteristics and medicating rules. Methods： The effects, natures,tastes and channel distributions were sorted through and concluded through retrieving clinical literatures of Chinese medical fumigation in the treatment of KOA in recent 15 years. Results： Totally 174 effective references were selected, involving 221 herbs; the cumulative frequency of wind-dampness dispelling drugs, blood-activating and stasis-removing drugs as well as deficiency tonifying drugs was 80.60%; the highest frequencies of drugs application were Chuanwu, Caowu, Danggui, Honghua and Shenjincao; the cumulative frequency of drugs with warm, flat and cold natures among four properties in TCM was up to 95.48%, and that of pungent, bitter and sweet drugs came to94.12%; the drug＇s channel distributions were mainly liver, spleen and kidney. Conclusion： The main medicines for KOA treatment by Chinese medical fumigation are wind-dampness dispelling drugs as well as blood-activating and stasis-removing drugs; treatment mainly focuses on removing pathogenic factors from the perspective of dispelling wind and dampness and dredging collaterals, activating blood circulation and removing blood stasis as well as expelling cold and stopping pain. Meanwhile, the flexible modification of the drugs can be implemented in clinic according to the syndromes.
出处
《西部中医药》
2015年第3期97-100,共4页
Western Journal of Traditional Chinese Medicine
基金
国家自然科学基金面上项目(编号81173286)
关键词
骨性关节炎
膝
中药熏洗
用药规律
文献研究
KOA
Chinese medical fumigation
medication regularity
literature study
