摘要
目的探讨儿童变应性鼻炎(AR)与腺样体肥大的关系,评价鼻用类固醇治疗儿童变应性鼻炎伴腺样体肥大的疗效。方法对照组为单纯腺样体生长儿童261例,其中腺样体肥大190例(72.7%)。观察组为变应性鼻炎伴腺样体生长儿童162例,其中腺样体肥大110例(67.2%)。两组均给予鼻用类固醇(丙酸氟替卡松喷剂)持续喷鼻3个月后于鼻内镜下复查。结果对照组并发腺样体肥大构成比为72.7%,观察组并发腺样体肥大构成比为67.2%,差异无统计学意义(χ2=1.16,P>0.05)。对照组采用鼻用类固醇治疗后有效腺样体体积减少112例(58.9%),观察组有效腺样体体积减小89例(80.9%)(χ2=19.04,P<0.01)。结论经鼻用类固醇治疗,变应性鼻炎伴腺样体肥大患儿腺样体体积减小程度较单纯腺样体肥大患儿明显。对变应性鼻炎合并腺样体肥大者可优先考虑应用鼻用类固醇激素。
Objective To evaluate the curative effect of steroid nasal spray on pediatric allergic rhinitis with adenoidal hypertrophy.Methods A total of 261 children with adenoids served as the control group,of them,190 children （72.7%）were with adenoid hypertrophy.A total of 162 children with allergic rhinitis and adenoids served as the ex-perimental group,of them,110 children（67.2%）were with adenoid hypertrophy.The two groups were both treated by Fluticasone propionate nasal spray （50 μg per nostril a day）for 3 months.Results Adenoidal hypertrophy incidence was 72.7% in the control group and 67.2% in the experimental group （χ2 =1.16,P 〉0.05）.112 （58.9%）patients in the control group and 89 （80.9%）patients in the experimental group had the adenoidal volume decreased （χ2 =19.04,P 〈0.01）.Conclusion After steroid nasal spray treatment,the adenoidal volume is much more decreased in the experimental group than in the experimental group.Steroid nasal spray is the first choice for children with allergic rhinitis and adenoidal hypertrophy.
出处
《山东大学耳鼻喉眼学报》
CAS
2015年第2期41-43,共3页
Journal of Otolaryngology and Ophthalmology of Shandong University
基金
广东省医学科学技术研究基金(A2013793)
