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长链非编码RNA在脑胶质瘤中的研究进展 被引量:4

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摘要 长链非编码RNA(long non-coding RNAs,lnc RNA)是一类长度超过200核苷酸,不编码蛋白的RNA总称。其通过多种方式参与基因表达调控,与肿瘤发生、发展密切相关。研究发现:lnc RNA在脑胶质瘤组织中异常表达,具有促进或抑制胶质瘤细胞增殖、侵袭等作用,与脑胶质瘤病人预后相关。本文就lnc RNA在脑胶质瘤研究进展作一综述,为进一步研究脑胶质瘤发病机制,寻找新的治疗靶点及预后指标提供新思路。
出处 《中国微侵袭神经外科杂志》 CAS 2015年第4期190-192,共3页 Chinese Journal of Minimally Invasive Neurosurgery
基金 国家自然科学基金项目(编号:81172398 81270038) 上海市科学技术委员会科研计划项目(编号:13ZR1414200)
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