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乌司他丁和奥曲肽对急性重症胰腺炎患者治疗效果分析 被引量:7

The analysis of ulinastatin and octreotide in treatment of acute severe pancreatitis
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摘要 目的对乌司他丁和奥曲肽对急性重症胰腺炎患者治疗效果进行分析探究。方法选取在我院接受治疗的86例急性重症胰腺炎患者,将其随机分为试验组和对照组,每组43例患者,对照组患者单独采用奥曲肽进行治疗,试验组患者采用乌司他丁和奥曲肽对患者进行治疗,对比分析两组患者的临床治疗效果及经治疗后的住院相关指标情况情况。结果两组患者采用不同的治疗方法进行治疗后,试验组患者的总有效率(90.70%)明显高于对照组患者的总有效率(69.77%),差异有统计学意义(P<0.05)。且试验组患者的腹痛缓解时间(1.4±0.4)d及平均住院时间(15.0±4.8)d明显低于对照组患者的腹痛缓解时间(4.1±1.1)d及平均住院时间(23.0±6.7)d,差异有统计学意义(P<0.05)。结论乌司他丁联合奥曲肽对急性重症胰腺炎患者治疗效果显著,住院时间短,安全可靠,值得推广应用。 Objective To explore the effect of ulinastatin and octreotide in treatment of acute severe pancreatitis. Methods 86 cases of patients with severe acute pancreatitis were selected from our hospital, and they were divided into two groups-control group and experimental group (each group had 43 cases), the control group patients were treated with octreotide alone, the experimental group patients were treated with Ulinastatin and octreotide, we compared two groups' in clinical treatment effect and related indicators of the situation after treatment. ResultsAfter treatment, the experimental group's total treatment efficiency was 90.70%, the control group's total treatment efficiency was 69.77%, and experimental group was better than the control group, and the difference were significantly (P〈0.05); In pain relief time, the experimental group was (1.4±0.4)d, the control group was (4.1±1.1)d, and experimental group was better than the control group, and the difference were significantly (P〈0.05); In length of stay, the experimental group was (15.0±4.8)d, the control group was (23.0±6.7)d, and experimental group was better than the control group, and the difference were significantly(P〈0.05).Conclusion Ulinastatin combined with octreotide had a good effect in treatment of acute severe pancreatitis, it can shorter hospital stay, and also it's safe and reliable for patients, so it can be widely applied in clinical.
作者 周春山
出处 《中国医药科学》 2015年第5期96-98,共3页 China Medicine And Pharmacy
关键词 乌司他丁 奥曲肽 急性重症胰腺炎 临床效果 Ulinastatin Octreotide Severe acute pancreatitis Clinical effect
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