摘要
连续性肾脏替代治疗(CRRT)显著影响大多数药物在机体内的药物代谢动力学特征,因此研究CRRT时药物的药物代谢动力学具有重要意义。本文对CRRT时抗菌药物药物代谢动力学研究现状及发展趋势进行分析和总结,为临床合理使用抗菌药物提供参考依据和实验基础。
Continuous renal replacement therapy (CRRT) can affect the pharmacokinetic characteristics of most drugs in the body, thefore it's important to study the pharmacokinetics of drugs at CRRT. This review analyzes and summarizes the research status and the development trend of antibacterial drugs pharmacokinetics under CRRT, and also provide reference and experimental basis for clinical rational use of antimicrobial agents.
出处
《兰州大学学报(医学版)》
CAS
2015年第2期7-14,共8页
Journal of Lanzhou University(Medical Sciences)
基金
科技部重大项目(2008ZXJ09014-010)