摘要
目的:探究对血清前列腺特异性抗原(PSA)<10.0μg/L者行经会阴饱和前列腺穿刺活检诊断前列腺癌的应用价值和临床意义,为临床前列腺癌的诊治提供参考。方法:选取医院2012年7月至2014年6月收治的138例行前列腺穿刺活检者作为研究对象,医院检查所有患者血清PSA<10.0μg/L。依据穿刺方法的不同将患者分为:经直肠穿刺组(A组,共39例)、经会阴12针穿刺组(B组,共48例)、经会阴饱和穿刺组(C组,共51例)。对比观察各组间患者活检阳性率和经不同手术方法穿刺活检后并发症的发生率。结果:138例患者经前列腺穿刺活检确诊前列腺癌25例。其中A组3例,阳性率7.69%;B组6例,阳性率12.50%;C组16例,阳性率31.37%。C组活检阳性率明显高于A组和B组,差异有统计学意义(P<0.05),A组和B组阳性率比较差异无统计学意义(P>0.05)。穿刺活检后共有32例患者出现术后并发症,总发生率为23.19%。其中A组18例,总发生率46.15%;B组6例,总发生率12.5%;C组8例,总发生率15.69%。A组并发症发生率明显高于B组和C组,差异有统计学意义(P<0.05),B组和C组并发症发生率比较差异无统计学意义(P>0.05)。结论:对于血清PSA<10.0μg/L的行穿刺活检诊断前列腺癌者,采用经会阴饱和前列腺穿刺活检法可以得到较为准确的诊断结果,同时术后并发症少,具有较高的安全性,值得在临床前列腺癌诊断上广泛应用。
Objectives： To explore the diagnostic value and clinical significance of transperineum saturation prostate biopsy for prostate cancer patients with serum prostate -specific antigen （PSA） 〈 10.0μg/ L, to provide reference for the clinical diagnosis and treatment of prostate cancer. Methods： The 138 patients received prostate biopsy in our hospital from July 2012 to June 2014 were selected as research objects, with serum PSA 〈 10.0μg / L. According to the method of puncture, patients were divided into transeeted biopsy group （group A, 39 cases） , transpefineal 12- needle aspiration （group B, 48 cases） and transperineal saturation biopsy group （group C, 51 cases）. The incidence of positive biopsy rate and post - biopsy complications of each group were compared. Results： Among the 38 patients underwent prostate biopsy, 25 cases were confirmed of prostate cancer, including 3 cases in group A （7.69%）, 6 cases in group B （12.50%） and 16 cases in group C （31. 37% ） ; the positive biopsy rate of group C was significantly higher than those in group A and group B, with statistically significant difference （P 〈 0.05 ） ; difference between group A and group B was not statistically significant （P 〉 0.05 ）. A total of 32 patients had postoperative complications, an overall incidence rate of 23. 19%, including 18 cases in group A （46. 15% ） ; 6 eases in group B （ 12.5% ） and 8 cases in group C （ 15.69% ） ; the incidence of complication in group A was significantly higher than those in group B and group C, with statistically significant difference （ P 〈 0. 05 ） ; difference between group B and group C was not statistically significant （ P 〉 0.05 ）. Conclusion ： Transperineal saturation prostate biopsy is of great diagnostic value for prostate cancer patients with serum PSA 〈 10.0μg/ L. With more accurate results, fewer complications, and high security, it is worth widely applying in clinical.
出处
《中国性科学》
2015年第4期47-50,共4页
Chinese Journal of Human Sexuality
