摘要
目的:探讨生长抑素在上消化道出血患者中的应用效果。方法:将138例上消化道出血患者随机数字表法分为观察组(n=69)与对照组(n=69),两组患者均给予禁食、抑制胃酸分泌、补液、低流量吸氧、输血等常规治疗,对照组在上述基础上加用泮托拉唑,观察组在对照组基础上加用生长抑素治疗,对比两组患者出血停止时间、临床效果及不良反应情况。结果:观察组患者上消化道出血停止时间显著短于对照组(P<0.01),同时总体有效率显著高于对照组(P<0.01),而两组在治疗过程中的药物不良反应发生率比较差异无统计学意义(P>0.05)。结论:生长抑素用于上消化道出血患者的治疗,能够快速有效止血,更好地减轻患者症状体征,安全可靠,值得推广。
Objective：To discuss the clinical effects of Somatostatin in the treatment of UGB. Method：138 patients with UGB were divided into the observation group（n=69）and the control group（n=69）,all the patients were given fasting,inhibiting gastric acid secretion,rehydration,low flow oxygen,blood transfusion and other conventional treatment,the control group were given Pantoprazole based on the conventional treatment,and the observation group were given Somatostatin based on the control group,then the hemostatic time,clinical effects and the adverse reaction were contrasted between the two groups. Result：The hemostatic time in the observation group was significantly shorter than the control group（P〈0.01）,the total effective rate of the observation group were significantly higher than the control group（P〈0.01）,but no significantly difference on the incidence of adverse reaction between the two groups（P〉0.05）. Conclusion：Somatostatin can quickly and effectively stop bleeding,better relieve symptoms and signs in the treatment of patients with UGB,it’s safe and reliable,worthy of promotion.
出处
《中国医学创新》
CAS
2015年第9期129-131,共3页
Medical Innovation of China
关键词
生长抑素
上消化道出血
临床疗效
Somatostatin
Upper gastrointestinal bleeding
Clinical effects
