摘要
目的：确定益母草颗粒剂的制备工艺。方法：以正交法优选益母草颗粒剂的最佳提取工艺条件，以最佳提取工艺条件进行制剂工艺研究。结果：取处方量的益母草中药，加10倍水煎煮2次，l h/次，合并煎液，静置，滤过，煎煮浓缩至相对密度为1.21-1.25（80℃）的清膏，加入适量的糊精及红糖粉以80%乙醇溶液为湿润剂制成颗粒，干燥，即得。结论：该制备方法简单可行，所得制剂质量稳定，可作为益母草颗粒剂的制备工艺。
Objective：To determine the feasible preparation technology of the YiMuCao （Leonurus Artemisia） granules. Methods：The optimum extraction conditions of YiMuCao granules were determined by orthogonal test and used to study the preparation technology. Results：YiMuCao selected by the recipe dosage was boiled twice in water 10 times the quantity of the herbs and 1 hour each time;two pieces of decoctions were mixed, quietly placed, filtered and boiled again to concentrate into the fluid with the relative density of 1.21-1.25 （80℃）, which was added amount of dextrin and brown sugar powders. The obtained mixture was granulated with 80%ethanol as wetting agent and dried, which was YiMuCao granules. Conclusion：The preparation technology was simple, convenient and feasible, and properties of the granules prepared by it were stable, so this technology can be used to prepare YiMuCao gran ules.
出处
《西部中医药》
2015年第2期27-29,共3页
Western Journal of Traditional Chinese Medicine
关键词
益母草
制备工艺
流浸膏
正交实验
YiMuCao
preparation technology
fluid extract
orthogonal
