摘要
目的比较新型植物灭螺剂-螺威(TDS)与50%氯硝柳胺乙醇铵盐(WPN)两种灭螺药物的两种现场灭螺方法的效果。方法计算机检索CNKI、Wan Fang Data、VIP和CBM数据库,纳入比较TDS和WPN现场灭螺效果的研究,检索时限均为建库至2014年4月。两位研究者按纳入与排除标准独立筛选文献、提取资料和评价纳入研究的方法学质量后,采用Rev Man 5.2软件进行Meta分析。结果共纳入9个研究。Meta分析结果显示:使用浸杀法灭螺时,与WPN相比,TDS施药后1 d、3 d的钉螺死亡率无明显差异,7 d的钉螺死亡率较低[RR=0.96,95%CI(0.93,1.00),P=0.04]。使用喷洒法灭螺时,WPN与TDS施药后1 d、3 d、7 d、15 d后的钉螺死亡率以及15 d后的活螺密度均无显著性差异。GRADE系统评分结果显示,证据水平为中等或低级。结论与WPN相比,TDS达到了天然源杀螺剂现场评价的要求,对钉螺的杀灭效果较好,其存量较大且价格低廉,值得进一步推广。
Objective To evaluate the two means of field molluscicidal effect by two different snail control drugs--new plant snail control agent luo-wei（Tea-seed distilled saponins, TDS） and 50% wettable powder of niclosamide（WPN）. Methods Such databases as CNKI, Wan Fang Data, VIP and CBM databases were searched for controlled trials about TDS vs. WPN for the molluscicidal effect from their establishment to April 2014. Two reviewers independently screened literature according to the inclusion and exclusion criteria, extracted data and assessed the methodological quality of included studies, and then meta-analysis was performed by using Rev Man 5.2 software. Results A total of 9 studies were included. The results of meta-analysis showed that： Snails mortality rate of TDS on 7 d was lower（RR=0.96, 95%CI 0.93 to 1.00, P=0.04） than WPN and no significant difference of the snails mortality rate on 1 d or 3 d between the two groups was found by means of immersion. Meanwhile, by means of spraying, there were no significant differences on the snails mortality rate on 1 d, 3 d, 7 d, 15 d between the two groups; densities of living snails on 15 d wasn＇t, either. Based on GRADE system, the evidence was at level B or C. Conclusion Compared with WPN, TDS has reached the requirements of the natural source twin-screw agent field evaluation. The molluscicidal effect of TDS is better, with its large stock and low price, it is worthy to do further popularization.
出处
《中国循证医学杂志》
CSCD
2015年第4期464-470,共7页
Chinese Journal of Evidence-based Medicine
关键词
螺威
氯硝柳胺乙醇铵盐
灭螺效果
系统评价
META分析
Luo-wei
Wettable powder of niclosamide
Molluscicidal effect
Systematic review
Meta-analysis
