摘要
[目的]观察普洱茶浓缩提取物对生长中大鼠营养生理功能的影响。[方法]将生长期SD大鼠40只随机分为4组,每组10只,分别为对照组、普洱茶浓缩提取物低剂量组、中剂量组和高剂量组。3个试验组分别按270、540和1 080 mg/kg体重灌胃,对照组用等量蒸馏水灌胃。6周后结束试验,观察体重变化、血常规、血生化等相关生理指标的变化。[结果]高剂量试验组大鼠终体重、肥胖指数均显著低于对照组(P<0.05),各试验组大鼠脂肪指数显著低于对照组(P<0.05)。中、高剂量组大鼠脑指数显著高于对照组。高剂量组大鼠红细胞、血小板显著高于对照组(P<0.05)。各试验组大鼠血清总蛋白、白蛋白及球蛋白均高于对照组,中、高剂量组与对照组有显著差异(P<0.05)。各试验组大鼠血清中瘦素含量、高密度脂蛋白含量显著高于对照组(P<0.05)。试验组大鼠甘油三酯、致动脉粥样硬化指数(AI)、血糖含量低于对照组,而抗动脉粥样硬化指数(AAI)高于对照组,但无显著差异(P>0.05)。[结论]普洱茶浓缩提取物可以有效控制大鼠体重增加,抑制大鼠腹部脂肪积累,升高血清瘦素和高密度脂蛋白,降低血清甘油三酯,从而进一步预防动脉粥样硬化的发生。
[ Objective ] To investigate the nutritional physiological functions of concentration extract of Pu-er tea（PCE）. [ Method ] 40 SD rats were randomly divided into four groups, control group, low-, middle-and high dosage of tea extract groups, 10 of each. Rats in the Pu-er tea treatment groups were orally given PCE in the dosage of 270,540, 1 080 mg,/kg respectively. All rats were pair-fed 6 weeks to observe changes of their physiological indexes. [ Result] The rats＇body weight, Lee＇s index in high-dosage group was significantly lower thanthat of the control group（ P 〈 0.05 ）. Fat index in all experimental groups was significantly lower than the control group （ P 〈 0.05 ）. Serum TP, ALB, GLB in the middle- and high-dosage experimental groups showed statistic significantly higher than that of the control group（ P 〈 0.05 ）. Content of serum leptin and HDL in all experimental groups were significantly higher than that of the control group （P 〈 0.05 ）. Serum TG, AI and blood sugar of all experimental groups were lower than the control group, while the AAI level higher than the control group, but with no significant difference （ P 〉 0.05 ）. [ Conclusion ] PCE can effectively control the body weight and body fat of rats. Serum leptin and HDL can be increased and serum TG decreased by PCE intake, which could potentially prevent the arteriosclerosis.
出处
《安徽农业科学》
CAS
2015年第12期387-390,共4页
Journal of Anhui Agricultural Sciences
关键词
普洱茶
浓缩提取物
营养生理功能
Pu-erh tea
concentration extract
Nutritional Physiological Functions
