摘要
目的观察滋阴益气中药减少成年男性肾病综合征复发的临床疗效。方法将100例男性肾病综合征患者按入组顺序单双号随机分为观察组和对照组,各50例。观察组患者给予西医常规治疗和滋阴益气中药,对照组给予常规西医治疗。治疗12个月后,观察相关实验室指标的变化,并随访18个月,观察两组患者的复发率。结果 18个月随访期结束后,观察组在各观察节点复发例数均低于对照组,总复发率为18.00%,显著低于对照组的62.00%(P<0.05);治疗后,两组患者血清总蛋白(TP)、血清白蛋白(ALB)、总胆固醇(TC)、三酰甘油(TG)及24 h尿蛋白均与本组治疗前比较,差异有统计学意义(P<0.05),而观察组各项指标改善更明显(P<0.05)。结论滋阴益气中药可显著降低成年男性肾病综合征复发率,值得临床进一步研究。
Objective To observe the curative effect of nourishing Yin and tonifying Qi Chinese medicine for reducing the relapse of adult male nephrotic syndrome. Methods 100 adult patients male with nephrotic syndrome were randomly divided into the observation group and the control group according to the odd or even number on the enrollment,50 cases in each group. The observation group was given the routine treatment of Western medicine and traditional Chinese medicine of nourishing Yin and tonifying Qi,while the control group was given the conventional treatment of Western medicine alone. The changes of related laboratory indexes after 12-month treat-ment were observed and the two groups were followed up for 18 months for observing the recurrent rate in the two groups. Results Comparing the recurrent rate after 18-month follow up in the two groups,the recurrent cases number at each observation pitch point in the observation group was lower than that in the control group,the total recurrence rate was 18. 00%,which was significantly lower than 62. 00% in the control group（ P 〈 0. 05）;TP,ALB,TC,TG and 24 h urine protein in the two groups had statistically significantly difference between before and after treatment（ P 〈 0. 05）;but the improvement of each index in the observation group was more obvious （ P 〈 0. 05）. Conclusion The traditional Chinese medicine of nourishing Yin and tonifying Qi can significantly reduce the recurrence rate of adult male patients with nephrotic syndrome,which is worthy of further study in clinic.
出处
《中国药业》
CAS
2015年第8期90-91,共2页
China Pharmaceuticals
关键词
肾病综合征
滋阴益气
成年男性
复发
nephrotic syndrome
nourishing Yin and tonifying Qi
male
recurrence
