摘要
目的了解贺州市孕产期艾滋病抗体检测、感染孕产妇及感染孕产妇母子抗艾滋病病毒药物应用与检测状况及变化趋势。方法利用国家预防艾滋病母婴传播管理信息网络直报系统,收集和整理贺州市2006—2012年孕产期艾滋病抗体、CD+4T淋巴细胞、病毒载量等检测信息、HIV感染孕产妇孕期、产时以及所生儿童应用抗逆转录病毒药物等相关信息。对相关数据进行描述性分析和年度趋势变化分析。结果 2006—2012年贺州市共有130 743例孕产妇接受艾滋病抗体检测,其中孕产妇HIV抗体检测率从2006年的88.68%上升至2012年的99.96%。7年中,贺州市共发现230例HIV感染孕产妇。2006—2012年分别有67.86%、70.59%、82.05%、82.14%、97.30%、100%和100%的感染孕产妇应用了抗病毒药物,并呈逐年上升趋势(χ2=6.30,P<0.05),感染产妇孕28周前(含28周)开始应用三联方案比例也呈逐年上升趋势;感染产妇所生婴儿抗逆转录病毒药物应用比例自2010年均达到100%。结论孕期抗体检测比例仍有待进一步提高。尽管感染孕产妇及所生婴儿抗病毒药物应用比例逐年上升,但感染产妇在孕早期抗病毒药物应用比例比较低,需要进一步提高孕早期抗体检测比例及感染产妇在孕早期抗病毒药物应用比例,从而减少母婴传播的风险。
Objective To learn the status and trends of HIV-antibody testing and the application of antiretroviral drugs during pregnant women in Hezhou.Methods Depending on management information system of prevention of mother-to-child transmission of HIV （PMTCT）information network and reporting system,information including HIV testing during pregnancy and delivery,antiretroviral drugs application in HIV-infected pregnant women and their infants,HIV co-infec-tion,HIV status among HIV infected pregnant women’s spouse were collected from 2006 to 2012 in Hezhou.The rate or ra-tio was described and the difference of HIV testing and ARVs taking among the mother-child pairs was tested by Chi-square. Results From 2006 to 2012,a total of 130 743 cases of pregnant women received HIV antibody testing,of which HIV tes-ting ratio of each year were raised from 88.68% to 99.96%.In those 7 years,230 pregnant women were positive in Hezhou, and ratio of ARVs application among HIV infected pregnant women were 70.59%,82.05%,67.86%,82.14%, 97.30% and 100%,respectively,which showed increasing year by year （χ2 =6.30,P 〈0.05）.The ratio of women who accepted triple ARV regimen before 28 weeks of gestation （28 weeks）was also raised from 2006 to 2012.For the in-fants of these women,the ratio of receiving drugs reached 100% since 2010.Conclusion The proportion of HIV-testing during pregnancy still needs improvement.Although the proportion of the HIV-infected pregnant women and their infants who received antiviral drugs increased year by year,the proportion is relatively lower in the early pregnancy,we should improve the early pregnancy antibody testing and antiviral drugs application,thereby reducing the risk of HIV mother to child trans-mission.
出处
《中国健康教育》
北大核心
2015年第3期270-272,共3页
Chinese Journal of Health Education
