摘要
目的:探讨抗抑郁治疗对下肢血管病变的2型糖尿病合并抑郁症患者的影响。方法:本研究选择2型糖尿病合并抑郁症患者100例,女性58例,男性42例,平均年龄(54±8)岁。全部受试者在血糖、血压、血脂控制达标基础上随机分为两组,抑郁症干预组和抑郁症非干预组,各50例。非干预组采用基线治疗;抑郁症干预组除维持基线治疗外,给予心里疏导和或给予氟哌噻吨美利曲辛片(2片/天)抗抑郁治疗,1年后所有患者再次进行下肢血管病变彩超检查,分析两组患者的下肢血管病变进展情况。结果:抑郁症干预组较抑郁症非干预组下肢血管病变进展显著减慢(P<0.05)。结论:抗抑郁治疗可以使2型糖尿病下肢血管病变患者明显获益。
Objective： To investigate the anti depression treatment in patients with type 2 diabetes mellitus complicated with depression effect on the lower extremity vascular disease. Methods This study selected 100 cases of type 2 diabetic patients with depression, 58 females, 42 males, mean age （54±8） years old. All of the subjects in the blood glucose, blood pressure, blood lipid control standards on the basis of depression were randomly divided into two groups, intervention group and non intervention group of depression, 50 cases in each. Non intervention group with baseline therapy; depressive intervention group in addition to the baseline treatment, to ease the mind or give Flupentixol and Melitracen Tablets（2piece/day） of antidepressant treatment in all the patients, 1 years after the re color Doppler ultrasound examination, lower extremity vascular disease. Analysis of the development of vascular lesions in the lower limbs of two groups of patients. Results： Depression group than in non intervention in depression group of lower extremity vascular disease were significantly decreased （P〈0.05）..Conclusion：The anti depression therapy can make the lower extremity vascular disease in type 2 diabetic patients with obvious benefit.
出处
《中国医药导刊》
2014年第7期1133-1134,共2页
Chinese Journal of Medicinal Guide
关键词
抑郁症
2型糖尿病
下肢血管病变
Depressive disorder
Type 2 diabetes
Lower extremity vascular disease
