摘要
目的对比分析合并慢性阻塞性肺疾病(COPD)的肺血栓栓塞症(PTE)患者的临床特点。方法搜集2008年12月至2013年6月武汉市中心医院收治的16例合并COPD的PTE的住院患者的基本信息、合并疾病、吸烟指数、临床表现等数据,与无合并COPD的PTE患者26例进行比较。结果相比无合并COPD组,合并COPD的PTE患者年龄偏大[(72±8)岁与(65±12)岁,P<0.05],吸烟指数较高[(338±361)支年与(183±299)支年,P<0.05],近期卧床史较少(6%与42%,P<0.05),心率>100次/min者比例较少(31%与65%,P<0.05),二氧化碳分压(PaCO2)相对较高[(46±14)mmHg与(31±6)mmHg,P<0.01],修订版日内瓦评分较低[(3.2±2.3)分与(7.0±2.5)分,P<0.01]。结论相比无合并COPD组,合并COPD的PTE患者年龄偏大,吸烟指数较高,PTE临床可能性评分低,其临床表现与无COPD合并的患者有一定区别但不够特异,诊断需谨慎。
Objective To compare the clinical characteristics of pulmonary thromboembolism（PTE）in patients with and without previously diagnosed chronic obstructive pulmonary disease（COPD）.Methods We analyzed 42 patients with confirmed PTE enrolled in our hospital from December 2008 to June 2013,and compare clinical features in patients with or without COPD.Results Compared with PTE patients without COPD,those with COPD were older[（72±8）yr vs（65±12）yr,P〈0.05],possessing higher smoking index [（338±361）cigarette-years vs（183±299）cigarette-years,P〈0.05],and less percentages of immobility and hear rate over100beat/min（6%vs 42%,P〈0.05,and 31%vs 65%,P〈0.05,respectively）,moreover PCO2 in PTE patients with COPD was higher than those without COPD [（46±14）mmHg vs（31±6）mmHg,P〈0.01],while revised Geneva score was lower[（3.2 ± 2.3）points vs（7.0 ± 2.5）points,P〈0.01].Conclusion PTE patients with COPD were older,had a higher smoking index and they were more likely to be stratified into low clinical probability of PTE than those without COPD,in addition their symptoms were not specifically different.
出处
《山西医药杂志》
CAS
2015年第5期503-505,共3页
Shanxi Medical Journal
基金
武汉市卫计委项目(WX13B07)
关键词
肺栓塞
肺疾病
慢性阻塞性
体征和症状
Pulmonary embolism
Pulmonary disease
chronic obstructive
Signs and symptoms
