摘要
目的:探讨菊形团形成性胶质神经元肿瘤(RGNT)的影像学特征,以提高对本病的认识。材料与方法回顾性分析10例(男∶女=3∶7,年龄介于8~45岁)经手术病理证实的RGNT患者的影像学资料。10例行MR平扫及增强扫描,其中3例行CT平扫。结果10例肿瘤发生部位呈多样性,肿瘤位于小脑蚓部的4例;第四脑室内的2例;小脑半球、脑桥、颈髓、胸-腰髓各1例。肿瘤实性的稍多(6例),囊实性者略少(4例)。MR表现,肿瘤实性部分于T1WI肿瘤呈稍低-等信号、T2WI呈稍高信号,囊性部分于T1WI呈低信号、T2WI呈高信号。增强强化形式多样,可呈不均匀轻度-中度强化(6例),环形强化(1例),局限性结节样(2例)、斑片样(1例)。8例肿瘤周边可见轻度水肿,1例中度水肿。4例伴有幕上梗阻性脑积水,1例伴有脊髓空洞。肿瘤平扫CT表现实性部分呈稍低密度,囊性部分呈低密度,2例内可见出血。结论 RGNT好发于年轻患者,女性偏多;发生部位、影像表现具有一定特点,而术前鉴别诊断时应考虑到该病的可能。
Objective: To study the radiographic features of rosette-forming glioneuronal tumor (RGNT), and enhance neuroradiologist’s awareness of this newly described tumor. Materials and Methods:The radiological images of 10 patients with pathologically proved RGNT were retrospectively analyzed. There were 3 males and 7 females, with the age between 8 to 45 years. Routine MR (10 cases) and CT (3 cases), contrast-enhanced MR (10 cases) were performed. Results: There were located in cerebellar vermis (4 cases), in the fourth ventricle (2 cases), in cerebellar hemisphere (1 case), in pons (1 case), in the cervical spinal cord (1 case), in thoracic and lumbar spinal cord (1 case).The solid component of the tumor showed slightly hypo-isointense on T1WI and slightly hyperintense on T2WI.The cystic component of the tumor appeared hypointense on T1WI and hyperintense on T2WI. The enhancement pattern was various, from mild to moderate heterogenous enhancement (6 cases), ring (1 case), or focal enhancement which is nodular (2 cases), spot-like (1 case). Eight cases showed mild peritumoural edema and 1 case showed moderate edema. Four cases accompanied with obstructive hydrocephalus and 1 case with syringomyelia. On plain CT scan, solid regions showed slightly low density, cystic regions appeared low density and 2 cases showed intratumoral bleeding. Conclusion:RGNT might occur in younger age and has mild female predilection. Imaging appearance of RGNT has certain characteristics and should be considered for differentiation.
出处
《磁共振成像》
CAS
CSCD
2015年第4期241-245,共5页
Chinese Journal of Magnetic Resonance Imaging
基金
国家自然科学基金项目(编号:81271541)
关键词
神经元
神经系统肿瘤
磁共振成像
病理学
Neurons
Nervous system neoplasms
Magnetic resonance imaging
Pathology