期刊文献+

观察左旋甲状腺素片对妊娠期亚临床甲状腺功能减退患者的临床治疗效果 被引量:17

下载PDF
导出
摘要 目的探析左旋甲状腺素片在妊娠期亚临床甲状腺功能减退患者中的应用效果及对妊娠结局的影响。方法 70例妊娠期亚临床甲状腺功能减退患者作为研究对象,随机分为观察组(36例)和对照组(34例)。对照组不进行正规治疗,观察组服用左旋甲状腺素片进行治疗,比较两组妊娠结局,包括流产率、早产率、胎儿窘迫发生率以及剖宫产率。结果两组流产率、胎儿窘迫发生率差异无统计学意义(P>0.05),观察组早产率、剖宫产率分别为2.8%(1/36)、22.2%(8/36),低于对照组的17.6%(6/34)和47.1(16/34),差异有统计学意义(P<0.05)。结论左旋甲状腺素片在妊娠期亚临床床甲状腺功能减退症患者中的应用可大幅降低早产率与剖宫产率,改善妊娠结局,效果显著。
作者 孙亚琴
出处 《中国实用医药》 2015年第10期140-141,共2页 China Practical Medicine
  • 相关文献

参考文献5

二级参考文献24

  • 1王军林,王长英,李红钊.原发性甲状腺功能减退症17例误诊分析[J].陕西医学杂志,2008,37(7). 被引量:5
  • 2鲁扬.妊娠合并甲状腺功能减退症的临床治疗[J].中国医师进修杂志,2006,29(1):32-33. 被引量:2
  • 3王允锋,杨慧霞.妊娠合并甲状腺功能低减患者的临床分析[J].中华妇产科杂志,2007,42(3):157-160. 被引量:38
  • 4Sdano MT, Falciglia M, Welge JA, et al. Efficacy of thyroid hormone suppression for benign thyroid nodules: meta-analysis of randomized trials[J]. Otolaryngol Head Neck Surg, 2005, 133(3):391-396.
  • 5Costante G, Crocetti U, Schifino E, et al. Slow growth of benign thyroid nodules after menopause: no need for long-term thyroxine suppressive therapy in post-menopausal women[J]. J Endocrinol invest, 2004, 27(1):31-36.
  • 6Cesareo R, Iozzino M, Isgro MA, et al. Short term effects of levothyroxine treatment in thyroid muhinodular disease[J]. Endocr J, 2010, 57(9):803-809.
  • 7Casey BM, Dashe JS, Wells CE, etal. Subclinical hypo- thyroidism and pregnancy outcomes[J]. Obstet Gynecol, 2005, 105(2): 239-245.
  • 8Blazer S, Moreh WY, Zccv HRM, etal. Maternal hypo- thyroidism may affect fetal growth and neonatal thyroid function[J]. Obstet Gyneeol, 2003, 102: 232-241.
  • 9Stagnaro-Green A,Abalovich M, Alexander E, et al. Guidelines of the American Thyroid Association for the diagnosis and management of thyroid disease during pregnancy and postpartum [ J ]. Thyroid ,2011,21 ( 10 ) : 1081-1125.
  • 10Glinoer D, Delange F. The potential repercussions of maternal fetal,and neonatal hypothyroxinemia on the progeny [ J] Thyroid 2000,10(10) :871-887.

共引文献65

同被引文献119

  • 1冯桂玲.对使用左旋甲状腺素片进行治疗的甲状腺功能减退症孕妇妊娠结局的分析[J].当代医药论丛,2014,12(14):235-235. 被引量:3
  • 2Yu B, Wang QW, Huang RP, et al. Establishment of a self-quential longi-tudinal reference intervals of maternal thyroid function during pregnancy [J]. Exp Bid Med,2010,235(4) :1212 - 1215.
  • 3Gharib H, Tuttle RM, Baskin HJ, et al. Subclinical thyroid dysfunc- tion: a joint statement on management from the American Association of Clinical Endocrinologists, the American Thyroid Association, and the Endocrine Society [ J ]. J Clin Endocrinol Metab, 2005, 90 (1) : 581-587.
  • 4Abalovich M, Amino N, Barbour LA, et al. Management of thyroid dysfunction during pregnancy and postpartum: an Endocrine Society Clinical Practice Guideline [ J]. J Clin Endocrinol Metab, 2007, 92 (8 Snppl): S1-S47.
  • 5Casey BM. Subclinical hypothyroidism and pregnancy [ J]. Obstet Gynecol Surv, 2006, 61 (6) : 415-420, 423.
  • 6Dai L, Deng C, Li Y, et al. Birth weight reference percentiles for Chinese [J]. PLoS One, 2014, 9 (8): e104779.
  • 7Chen LM, Du WJ, Dai J, et al. Effects of subclinical hypothyroid- ism on maternal and perinatal outcomes during pregnancy: a single- center cohort study of a Chinese population [ J]. Plos One, 2014, 9 (10): 1-8.
  • 8Casey BM, Dashe JS, Wells CE, et al. Subclinical hypothyroidism and pregnancy outcomes [ J]. Obstet Gynecol, 2005, 105 (2) : 239 -245.
  • 9Benhadi N, Wiersinga WM, Reitsma JB, et al. Higher maternal TSH levels in pregnancy are associated with increased risk for miscar- riage, fetal or neonatal death [J]. Eur J Endocrinol, 2009, 160 (6) : 985-991.
  • 10Cleary- Goldman J, Malone FD, Lambert- Messerlian G, et al. Maternal thyroid hypofunction and pregnancy outcome [J]. Ob- stet Gynecol, 2008, 112 (1) : 85-92.

引证文献17

二级引证文献128

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部