摘要
目的：探讨丙基硫氧嘧啶联合地塞米松治疗甲状腺功能亢进的临床效果。方法回顾性分析2012年1月-2013年12月在本院治疗的甲状腺功能亢进患者48例的临床资料，其中23例采用丙基硫氧嘧啶联合地塞米松治疗，为研究组，25例患者采用丙基硫氧嘧啶治疗，为对照组。治疗8周后，比较两组的临床疗效。结果治疗后，研究组的甲状腺体积显著小于对照组，症状消失时间、指标恢复正常时间均短于对照组（P〈0.01）。治疗后，两组的FT3、FT4、TT3、TT4水平与治疗前比较均显著下降（P〈0.01）；研究组治疗后的FT3、FT4、TT3、TT4水平均显著低于对照组（P〈0.05）。结论丙基硫氧嘧啶联合地塞米松治疗甲状腺功能亢进具有较好的临床效果，值得临床推广。
Objective To discuss clinical effect of propylthiouracil combined with hexadecadrol treating hyperthy-roidism. Methods Clinical data of 48 cases with hyperthyroidism treated in our hospital from January 2012 to Decem-ber 2013 were analyzed.Among them,23 cases were treated with propylthiouracil combined with hexadecadrol and were selected as study group,while 25 cases were treated with propylthiouracil and were selected as control group.After 8 weeks treatment,clinical efficacy of two groups was compared. Results After treatment,thyroid volume of study group was smaller than that of control group,and time of symptom disappearing,index returning to normal of study group was shorter than that of control group respectively （P〈0.01）.FT3,FT4,TT3,TT4 level were decreased after treatment compared with before treatment （P〈0.01）;FT3,FT4,TT3,TT4 level of study group were lower than those of control group （P〈0.05）. Conclusion Propylthiouracil combined with hexadecadrol for hyperthyroidism shows good clinical efficacy,and it is worthy of clinical promotion.
出处
《中国当代医药》
2015年第10期133-135,共3页
China Modern Medicine
