摘要
目的:探讨不同三联疗法根除幽门螺旋杆菌(HP)阳性胃溃疡患者的疗效。方法:收集90例HP阳性胃溃疡患者作为研究对象。按随机数字表法分为两组,研究组45例和对照组45例。研究组患者45例使用奥美拉唑+阿莫西林+呋喃唑酮;对照组患者45例使用枸橼酸铋钾+阿莫西林+呋喃唑酮。用胃镜检测两组患者治疗前以及治疗后HP阳性率。结果:两组患者治疗前HP阳性率差异无统计学意义(P>0.05),治疗后HP阳性率差异有统计学意义(P<0.05)。研究组和对照组治疗前症状评分分别为2.85±1.26分、2.79±1.02分,差异无统计学意义(P>0.05);研究组和对照组治疗后症状评分分别为0.47±0.06分、1.23±0.87分,差异有统计学意义(P<0.05)。结论:我们认为奥美拉唑+阿莫西林+呋喃唑酮治疗HP阳性胃溃疡者疗效肯定,值得临床推广。
Objective:To explore efficacies of different triple therapies on eradication of Helicobacterpylori ( HP) for HP posi-tive patients with gastric ulcer. Methods:90 HP positive gastric ulcer patients were selected as the research objects and divided into 2 groups according to random number table method, research group (45 cases) and control group (45 cases). The research group used Omeprazole + Amoxicillin + Furazolidone;while the control group took bismuth potassium citrate + Amoxicillin + Furazolidone. With gastroscope, the HP positive rates of the two groups before and after the treatment were examined. Results: There was no statistical difference in the HP positive rate between the two groups before the treatment; however, there was a statistical difference in the HP positive rate after the treatment (P<0. 05). The symptom scores of research group and control group before the treatment were 2. 85± 1. 26 and 2. 79±1. 02, respectively;and the difference was not statistically significant (P>0. 05). While, the symptom scores of re-search group and control group after the treatment were 0. 47±0. 06 and 1. 23±0. 87 respectively; and the difference was statistically significant (P>0. 05). Conclusions:It is considered that Omeprazole + Amoxicillin + Furazolidone has a certain effects on HP posi-tive gastric ulcer patients, and is worthy of clinical promotion.
出处
《中国民康医学》
2015年第9期21-22,共2页
Medical Journal of Chinese People’s Health
关键词
三联疗法
幽门螺旋杆菌
胃溃疡
Triple therapy
Helicobacter pylori
Gastric ulcer
