摘要
目的 评价γ干扰素释放试验（IGRAs）早期诊断肺结核疾病的效能.方法 取120例肺结核病人（实验组）,健康体检者60例（对照组）,对比GRAs、结核菌素皮试（TST）检测结果.结果 IGRAs用于肺结核诊断的敏感性、特异性分别为90.83％、90.55％,阳性、阴性预测值分别为97.11％、48.73％,Yuden指数0.835,TST上述指标分别为62.34％、71.67％、90.42％、24.25％、0.191,提示IGRAs诊断结核病的效能优于TST （P＜0.05）.结论 IGRAs对肺结核具有较高的诊断效能,可予以推广.
Objective To evaluate the diagnostic efficacy of interferon gamma release test （IGRAs） for early diagnosing pulmonary tuberculosis disease.Methods 120 patients with pulmonary tuberculosis （an experimental group） and 60 healthy controls （a control group） were chosen.Thte results of IGRAs and tuberculin skin test （TST） were compared between the two groups.Results The sensitivity,specificity,positive and negative predictive values,and the Yuden index of IGRAs were 90.83%,90.55%,97.11%,48.73%,and 0.835 and those of TST were 71.67%,62.34%,90.42%,24.25%,and 0.191,respectively,suggesting that IGRAs was more effective than TST for diagnosing tuberculosis （P〈0.05）.Conclusions IGRAs has a high diagnostic efficacy for pulmonary tuberculosis and should be clinically generalized.
出处
《国际医药卫生导报》
2015年第9期1229-1230,共2页
International Medicine and Health Guidance News
关键词
肺结核
IGRAs
诊断效能
Pulmonary tuberculosis
IGRAs
Diagnostic efficacy
