摘要
目的比较单纯使用高血压治疗药物吲达帕胺与联合使用苯溴马隆和吲达帕胺对血压和尿酸的影响。方法随机将350例伴高尿酸血症的高血压患者分为二组,其中单纯使用吲达帕胺组175例,苯溴马隆与吲达帕胺联合使用组175例。观察二组患者血压、血尿酸和尿尿酸变化。结果联合用药组患者血尿酸值和尿尿酸值较单纯用药组相比,有显著性降低(P<0.05);联合用药组患者血压值恢复正常的人数与单纯用药组相比,有显著性提高(P<0.05)。结论苯溴马隆与吲达帕胺联合使用对改善高血压和高尿酸血症比单纯使用吲达帕胺疗效好。
Objective To compare the different action on blood pressure and uric acid effects of the single hypertension treatment drug indapamide and the combination of benzene bromide malone and indapamide. Methods There were 350 patients in the clinical trial,who were divided randomly into two groups.175 patients were in the single drug indapamide treatment group,another 175 patients in the combination of benzene bromide malone and indapamide.The change of blood pressure,blood uric acid and urine uric acid of patients were detected.Results The value of blood uric acid and urine uric acid in the combination group of patients was significantly reduced compared to the single drug group.The amount of blood pressure re-turned to normal in the combination group was improved compared with them in the single drug group. Conclusions The combination of benzene bromide malone and indapamide for treating hypertension and hy-peruricemia is better than the single drug.
出处
《中国煤炭工业医学杂志》
2015年第4期563-565,共3页
Chinese Journal of Coal Industry Medicine
关键词
苯溴马隆
吲达帕胺
联合用药
血清尿酸
高血压
Benzene bromide Malone
Indapamide
Combination treatment
Blood uric acid
Hypertension
