摘要
目的:探讨血清β-人绒毛膜促性腺激素(β-h CG)雌二醇(E2)和孕酮(P)测定对异位妊娠早期诊断,异位妊娠保守治疗方法选择及疗效的价值。方法:选择异位妊娠患者150例(A组),正常宫内早孕者100例(B组)。采用化学发光法测定并比较两组血清β-h CG、E2和P的含量;根据血中β-h CG、E2、P的含量,给予药物保守治疗,判断β-h CG、E2、P对异位妊娠治疗方案选择的意义;比较药物保守治疗成功患者血清β-h CG和P水平下降至正常范围内分别需要的时间;分析治疗前不同血清β-h CG、E2和P水平与治疗结局的关系。结果:A组血清β-h CG、E2和P水平均低于B组,差异均有统计学意义(P<0.05);药物保守治疗成功患者的血清P水平下降至正常所需要时间少于β-h CG下降至正常值所需的时间,E2、P水平越低,成功率越高。结论:血清β-h CG、E2和P水平有助于异位妊娠早期诊断。动态测定血清P是一种优于血清β-h CG的评估异位妊娠保守治疗效果的检测。根据血中β-h CG、E2、P的含量为早期异位妊娠的治疗方案的选择提供量化指标。
Objective： To investigate β -serum human chorionic gonadotroPin （β -hCG ） estradiol （ E2 ） and Progesterone （ P ） the determination of the early diagnosis of ectopic pregnancy, ectopic pregnancy conservative treatment selection and therapeutic value.Method： 150 cases of ectopic pregnancy were selected as the group A, 100 cases of normal intrauterine pregnancy were selected as the group B.The β -hCG, E2 and P were determined by chemil According to β-hCG, E2, P content in the blood, given conservative medical treatment, determined β-hCG, E2, P ectopic pregnancy treatment options significance.Compared successful conservative treatment group decreased serum [3 -hCG and P levels were within the normal range to the time required.The different of pre-treatment serum β -hCG, E2 and P levels and treatment outcome relationship were analyzed.Result： The serum β -hCG , E2 and P in the group A were lower than the group B, the differences were statistically significant （ P〈0.05 ） .Conservative treatment decreased serum P drug levels to normal less than the time required β -hCG drops to normal time required, the lower the P, E2 level, the success rate more high.Conclusion： Serum β-hCG, E2 and the level of P is helpful to early diagnosis of ectopic pregnancy; serum P determination is a dynamic detection effect of conservative treatment of ectopic a superior evaluation of serum β -hCG of pregnancy; according to the content of blood β -hCG, E2, P for the treatment of early ectopic pregnancy options provide quantitative indexes.
出处
《中国医学创新》
CAS
2015年第12期119-122,共4页
Medical Innovation of China
基金
江西省赣州市科技局科技计划项目(GZ2014ZSF382)
关键词
绒毛膜促性腺激素
孕酮
雌二醇
异位妊娠
保守治疗
疗效监测
Chorionic gonadotropin
Progesterone
Estradiol
Ectopic pregnancy
Conservative treatment
Efficacy monitoring
