摘要
Objective：To summarize the mechanism of acupuncture in treating perimenopausal syndrome （PMS） from the aspects of reproductive endocrinology, immune system, neuroendocrine, the metabolism of free radicals and bone, and the effect of lipid. Methods： The databases including MEDLINE, EMBASE, CNKI, Wanfang, and CQVIP were searched from the launch of each database to June 2014 for relevant papers involving clinical and laboratory researches about PMS treated with acupuncture. Results： Acupuncture is a safe, effective, and scientific method in treating PMS, and the efficacy is significant. Conclusion： Considering the limits of previous studies, future research should use high technologies such as molecular biology and genetic testing, and adopt multicenter randomized controlled study method to evaluate the efficacy of acupuncture in treating female PMS, and to further explore the mechanism of acupuncture in treating PMS.
目的:从生殖内分泌、免疫系统、神经内分泌、自由基和骨的新陈代谢、血脂改变的角度,总结针刺治疗围绝经期综合征的机制。方法:检索了截止到2014年6月发表的临床和实验的针刺治疗围绝经期的研究,检索数据库包括MEDLINE,EMBASE,CNKI,万方和重庆维普。结果:针刺治疗围绝经期综合征是安全的、有效的、科学的,疗效是显著的。结论:以前的研究存在一定的局限性,以后再开展研究时,应采用诸如分子生物学、基因检测等高科技,也应开展更多的随机对照临床试验来评估针刺治疗围绝经期综合征的疗效,进一步探讨针刺治疗围绝经期综合征的机制。
