摘要
托法是中医外科内治三大法则之一,而透脓散作为透托法的代表方,已广泛运用于外科浅部化脓性疾病、内脏化脓性疾病,还可用于内科、妇产科等疾病,但从现代医学角度来说,透脓散是通过何种机制实现这些治疗作用的?为此,本文通过对近年来关于透脓散实验研究的相关文献回顾与归纳,重点展示了透脓散的功效研究、抗化脓性感染、抗肿瘤、抗胃溃疡、组方药物药理及研究方法的研究现状。总结了其存在的不足,即透脓散作用机制实验研究处于起步阶段,参考资料甚少,明显滞后于临床应用。同时已初步证实了透脓散用于化脓性感染的效用与科学性,并为其临床运用与实验研究开拓了新的领域。最后笔者对透脓散作用机制的实验研究方向与前景进行了展望。
Tuo-Fa （TF） is one of three internal treatment rules in traditional Chinese medicine （TCM） surgery. Tou- Nong-San （TNS） is the representative prescription of Tou-Tuo-Fa （TTF）, which has been widely used in surgical superficial pyogenic disease, visceral suppurative disease, as well as diseases of internal medicine and gynecology. However, from the perspective of modern medicine, how does TNS achieve these therapeutic effects？ Therefore, this article reviewed and summarized related literatures on experimental researches of TNS in recent years. It mainly showed its therapeutic effect, anti-pyogenic infection, anti-tumor, anti-gastric ulcer, prescription drug pharmacology and research method of TNS. The existed shortcomings were also summarized, which included the experimental study on TNS was in the initial stage with few reference materials and obvious lagged behind the clinical practice. Meanwhile, the effect and scientifieity of TNS on pyogenic infection had been initially verified. It developed new field for its clinical application and experimental study. At last, the author expressed views on the experimental research direction and prospect of TNS action mechanism.
出处
《世界科学技术-中医药现代化》
2015年第1期205-208,共4页
Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology
基金
内蒙古自治区科技厅自然科学基金项目(2014MS0838):透脓散对中性粒细胞表面Fc受体
C3b受体的影响
负责人:石志强
内蒙古自治区卫生和计划生育委员会医疗卫生科研计划项目(201302031):透托法对浅部化脓性感染趋化因子C5a
LTB4影响的研究
负责人:肖成
关键词
透脓散
透托法
作用机制
实验研究
综述
Tou-Nong-San, Tou-Tuo-Fa, action mechanism, experimental research, review
