期刊文献+

鼻咽癌患者调强放疗后口干燥症的调查分析 被引量:3

原文传递
导出
摘要 目的探讨鼻咽癌患者调强放疗后口干燥症的严重程度及其对日常生活的影响。方法 101例鼻咽癌患者接受调强放疗后,于3、6、12、18、24及24个月以上复查时进行口干问卷调查,每个时间点口干燥症的发生情况,比较每个时间点口干燥症的发生情况。记录放疗后患者自觉口干好转时间。结果 101例患者治疗前全部无口干,颌下腺3受照前的平均体积为6.8 cm,患侧的颌下腺受照射的平均剂量为(5 164±820)c Gy。健侧颌下腺平均剂量(4 569±722)c Gy,放疗后3个月患者口干燥症最严重,其次是放疗后6个月,经比较差异均有统计学意义(P<0.01)。放疗后12、18、24及24个月以上患者的口干燥症情况差异无统计学意义(P>0.05)。结论鼻咽癌患者口干燥症发生率随放疗结束时间延长而降低,并且随着放疗时间延长,口干燥症严重程度减轻。
出处 《广东医学院学报》 2014年第6期798-800,共3页 Journal of Guangdong Medical College
基金 国家自然科学基金资助项目(No.81272575)
  • 相关文献

参考文献17

  • 1崔甜甜,吴少雄,韩非,卢丽霞,黄劭敏,邓小武,卢泰祥,赵充.鼻咽癌调强放疗对腮腺功能的影响[J].中华放射肿瘤学杂志,2009,18(3):167-169. 被引量:10
  • 2郭蕊,孙颖,黄劭敏,尹文晶,唐玲珑,刘立志,林爱华,马骏.鼻咽癌容积旋转调强放疗与常规静态调强放疗的剂量学对比研究[J].中山大学学报(医学科学版),2012,33(6):835-840. 被引量:23
  • 3Murdoch-Kinch C A, Kim H M, Vineberg K, et al. Dose-effect relationships for the submandibular salivary glands and implicationsfor their spring by intensity modulated radiotherapy[J]. Int J Radiat One Biol, 2008, 72(2):373-382.
  • 4Wijers O B, Levenday P C, Braaksma M M, et al. Patients with head and neck cancer cured by radiation therapy:a survery of the dry mouth syndrome in long-term survivors [J]. Head Neck, 2002, 24(8): 737-747.
  • 5刘学奎,曾宗渊,洪明晃,张爱兰,崔念基,陈福进.鼻咽癌放疗后口干燥症的临床分析[J].癌症,2004,23(5):593-596. 被引量:12
  • 6Mira J G, Wescott W B, Starcke E N, et al.Some factors influencing salivary function when treating with radiotherapy[J]. Int Radiat Oncol Biol Phys, 1981, 7(4):535-541.
  • 7Heather D P, Robert J A, Christopher G M, et al.Late Xerostomia after intensity-modulated radiation therapy versus conventional radiotherap [J]. Am J Clin Oncol, 2005, 28(4):351-358.
  • 8Meirovitz A, Murdoch-Kinch C A, Scipper M, et al. Grading xerosto- mia by physicians or by patients after IMRT [J]. Int J Radiat Oncol Biol Phys, 2006, 66(2):445-453.
  • 9Jensen K, Jensen A B, Grau C, et al. The relationship between observer-based and patient assessed symptom severity after treatment for head and neck cancer [J]. Radiother Oncol, 2006, 78(3):298-305.
  • 10Beetz I, Schilstra C, Burlage F R, et al. Development of NTCP models for head and neck cancer patients treated with three- dimensional conformal radiotherapy for xerostomia and sticky saliva: The role of dosimetric and clinical factors[J]. Radiotherapy and Ontology, 2012, 105(1): 86-93.

二级参考文献54

  • 1赵充,韩非,卢丽霞,黄劭敏,林承光,邓小武,卢泰祥,崔念基.调强适形放射治疗对局部晚期鼻咽癌的临床疗效[J].癌症,2004,23(z1):1532-1537. 被引量:58
  • 2赵充,卢丽霞,韩非,卢泰祥,黄劭敏,林承光,邓小武,崔念基.122例鼻咽癌单纯根治性调强放疗疗效分析[J].中华放射肿瘤学杂志,2006,15(5):364-368. 被引量:34
  • 3关淑妮.放射性龋的产生与预防[J].广东牙病防治,1996,4(3):57-58. 被引量:4
  • 4Bjordal K, Kaasa S, Mastekaasa A. Quality of life in patients treated for head and neck cancer:a follow-up study 7 to 11 years after radiotherapy. Int J Radiat Oncol Biol Phys, 1994,28:847-856.
  • 5Leveque FG, Montgomery M, Potter DA, et al. Multicenter, randomized, double-blind, placebo-controlled, dose-titration study of oral pilocarpine for treatment of radiation-induced xerostomia in head and neck cancer patient. J Clin Oncol, 1993, 11: 1124- 1131.
  • 6Johnson JT, Ferretti GA, Nethery WJ, et al. Oral pilocarpine for post-irradiation xerostomia in patients with head and neck cancer. N Eng J Med, 1993,329:390-395.
  • 7Nishimura Y, Nakamatsu K, Kanamori S, et al. Importance of mean dose and initial volume ofparotid glands in xerostomia of patients with head and neck cancer receiving IMRT. Int J Radiat Oncol Biol Phys ,2004 ,60:522.
  • 8Kauko S,Manri K,Juhani C,et al. Intensity modulated radiotherapy for head and neck cancer: evidence for preserved salivary gland function. Radiother Oncol,2005 ,74 :251-258.
  • 9Clifford C, Navneet M, Chih-jen H, et al. Intensity-modulated radiation therapy reduces late salivary toxicity without compromising tumor control in patients with oropharyngeal carcinoma:a comparison with conventional techniques. Radiother Oncol,2001,61:275- 280.
  • 10Lee N, Xia P, Quivey JM, et al. Intensity-modulated radiotherapy in the treatment of nasopharyngeal carcinoma: an update of the UCSF experience. Int J Radiat Oncol Biol Phys,2002,53:12-22.

共引文献56

同被引文献41

引证文献3

二级引证文献20

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部