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风湿性多肌痛的诊断与治疗进展 被引量:4

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摘要 风湿性多肌痛(polymyalgia rheumatica,PMR)是50岁以上老年人常见的炎症性风湿性疾病,是一种具有多种临床表现的综合征.Forestier等在1953年报道了第1例PMR[1].PMR的临床表现主要为近端肢体炎性疼痛[2];以肩胛区、臀部及颈部肌肉疼痛及晨僵为主要特征,疼痛可放射到肘部或膝部,通常僵硬持续30 min以上,常出现于早晨或长久休息后.上述症状持续1个月,患者一般健康状况下降,急性期应答反应增强,如血沉(ESR)、C反应蛋白(CRP)升高.40%~50%的PMR患者通常呈对称性的症状.肌痛虽然是PMR患者的主要特征,但并没有典型的肌肉炎症.另外,PMR还可表现为疲倦、乏力、厌食、体重减轻及发热.最新观点认为,PMR是一个良性的对类固醇治疗高度敏感的疾病,其经低剂量的糖皮质激素连续治疗12 ~ 24个月可完全治愈(消退)[3].
出处 《内科急危重症杂志》 2015年第2期146-149,151,共5页 Journal of Critical Care In Internal Medicine
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