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抗癫痫药对育龄期女性癫痫患者生殖相关激素的影响观察

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摘要 目的:探讨抗癫痫药对育龄期女性癫痫患者生殖相关激素的影响。方法:选择我院于2013年4月至2014年6月期间新诊断为癫痫的60例育龄期妇女作为研究对象,分为3组,分别为丙戊酸钠组、卡马西平组、苯妥英钠组,三组患者均接受相应药物治疗,比较治疗前、后两组患者的激素变化、月经及卵巢情况。结果:三组患者服药三个月后,与服药前相比,FSH、PRL、LH、E2的检查指标均出现了明显变化,同组患者服药前与服药后相比,各指标差异均显著, P<0.05。结论:丙戊酸钠、卡马西平、苯妥英钠三种药物均对女性生殖相关激素存在较大影响,临床应用抗癫痫药物时需注意用药剂量及药物种类。
作者 耿直
出处 《中外女性健康研究》 2015年第5期68-69,共2页 Women's Health Research
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