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干细胞治疗糖尿病性勃起功能障碍的研究进展

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摘要 糖尿病性勃起功能障碍(diabetic erectile dysfunction,DED)发病机制复杂,其发病机制与多种病理生理变化相关,如神经病变、内皮素及其受体、NO合成障碍、糖基化终末产物、氧自由基等,这些变化使得勃起相关的平滑肌、内皮细胞及神经组织受到损伤。目前,干细胞对糖尿病性勃起功能障碍的修复和保护作用的临床前研究已成为热点。本文综述了骨髓间充质干细胞、脂肪源性干细胞、尿源性干细胞等在治疗DED方面的研究进展。
作者 叶德川 陈明
机构地区 东南大学医学院
出处 《国际泌尿系统杂志》 2015年第3期421-424,共4页 International Journal of Urology and Nephrology
基金 国家青年自然基金(编号:81300472)
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