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非ST段抬高型心肌梗死预后的影响因素研究

Influencing factor study on prognosis of non-ST-segment elevation myocardial infarction
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摘要 目的:探析非ST段抬高型心肌梗死(NSTEMI)预后的相关影响因素。方法回顾性分析本院2010年1月-2014年1月收治的82例NSTEMI患者的临床资料,统计随访6个月的心血管事件,包括主要心血管事件及次要复合心血管事件,采用单因素和多因素分析影响预后的因素。结果心血管事件发生率为58.5%(48/82),其中主要心血管事件发生率为3.6%(3/82),次要复合心血管事件发生率为54.9%(45/82)。单因素分析显示,预测NSTEMI患者6个月时心血管事件的相关因素包括冠心病史和糖尿病,差异均有统计学意义(P〈0.05);Cox回归分析显示,NSTEMI患者6个月时主要心血管事件相关因素为cTnI≥0.8μg/L、白细胞水平及入院静息心率〉100/min,差异均有统计学意义(P〈0.05);多因素Logistic回归分析发现,NSTEMI患者6个月时次要复合心血管事件相关因素为使用抗心律失常药和入院静息心率〉100/min,差异均有统计学意义(P〈0.05)。结论影响NSTEMI患者预后的相关因素包括冠心病史、糖尿病、cTnI≥0.8μg/L、白细胞水平升高及入院静息心率〉100/min,影响次要复合心血管事件的因素包括使用抗心律失常药和入院静息心率〉100/min。 Objective To explore relevant factor on prognosis of non-ST-segment elevation myocardial infarction (NSTEMI). Methods Clinical data of 82 patients with NSTEMI admitted to our hospital from January 2010 to January 2014 were retrospectively analyzed.Cardiovascular event during 6-month follow-up were collected,mainly including primary cardiovascular events and secondary and complex cardiovascular events.Influencing factor for prognosis were analyzed by univariate analysis and multivariate analysis. Results Incidence rate of cardiovascular event was 58.5%(48/82),in which incidence of primary cardiovascular event was 3.6%(3/82),and incidence of secondary cardiovascular events was 54.9%(45/82).Univariate analysis showed that history of coronary heart disease and diabetes were predicted to be relevant factors for cardiovascular events at the sixth month for patients with NSTEMI,with statistical difference (P〈0.05).Cox regression analysis showed that relevant factors for primary cardiovascular events at sixth months for pa-tients with NSTEMI were cTnI≥0.8μg/L,leukocyte level and resting heart rate upon admission〉100/min,with statistical difference(P〈0.05).Multivariate Logistic regression analysis showed that relevant factors for secondary and complex car-diovascular events at sixth months for patients with NSTEMI were administration of antiarrhythmic drugs and resting heart rate upon admission〉100/min,with statistical difference (P〈0.05). Conclusion Relevant influencing factors for prognosis of patients with NSTEMI include history of coronary heart disease,diabetes,cTnI〉0.8μg/L,increased leukocyte level and resting heart rate upon admission〉100/min,and influencing factors for secondary and complex cardiovascular events include administration of antiarrhythmic drugs and resting heart rate upon admission〉100/min.
作者 曾勇
出处 《中国当代医药》 2015年第13期54-56,59,共4页 China Modern Medicine
关键词 非ST段抬高型心肌梗死 预后 因素 Non-ST-sement elevation myocardial infarction Prognosis Factor
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