摘要
近年来,转录组学技术及其在水产动物中的研究备受研究者的广泛关注。转录组学技术主要有基于杂交技术和测序技术为基础的两大类技术;两类技术在水产动物的转录组学研究中均得到了广泛运用。尤其是二代测序技术的出现使得水产动物的转录组学研究达到了前所未有的热度。本实验综述了近年来水产动物在免疫应答、生长发育、生物进化和毒理学方面的转录组学研究进展。在综述已有成果的基础上,分析了转录组学技术自身存在的局限性和现阶段转录组学在水产动物研究中面临的问题与挑战,并对未来水产动物转录组学研究趋势进行了展望。
There is a growing interest for the progress and application of transcriptomics technology in recent years. Two types of techniques, including hybridization-or sequence-based method, have been developed for transcriptome investigations. With the emergence of next-generation sequencing techniques, those technologies have been widely used in the genetic studies of economic traits and molecular-aided selections for aquatic animals. This review has briefly summarized the progress of transcriptomic researches in aquaculture, involving immune response, growth, development, evolution and toxicology. Meanwhile, we have discussed challenges in both transcriptomic technologies and elaborate applications in aquaculture and analyzed prospects of further development of transcriptome researches on aquatic animals.
出处
《水产学报》
CAS
CSCD
北大核心
2015年第4期598-607,共10页
Journal of Fisheries of China
基金
国家自然科学基金(U1205122
31402302)
中央高校基本业务费专项(XDJK2015C034
XDJK2014C152)
关键词
水产动物
转录组学
基因表达
生物信息学
aquatic animal
transcriptomics
gene expression
bioinformatics
