摘要
在临床工作中,随着广谱抗生素的大量使用,伪膜性肠炎(PMC)的发病率逐年提高。难辨梭状芽孢杆菌是其主要致病菌,通过粪-口途径传播,其主要临床表现为轻重不一的腹泻。PMC可通过临床症状、实验室检查、内镜检查等手段进行早期诊断,并进行早期积极治疗以预防其反复发作。目前其微生态治疗,尤其是难辨梭状芽孢杆菌疫苗的研制将会成为PMC治疗新的研究方向。
Due to the massive use of broad-spectrum antibiotics in clinic,the incidence of pseudomen-braneouscolitis（ PMC） has increased dramatically.Clostridium difficile is the main pathogenic bacteria of PMC,that it is infected through the fecal-oral route,with main clinical manifestation of different levels of diar-rhea.Pseudomenbraneouscloitis can be early diagnosed by clinical symptoms,laboratory examination and endoscope.And early treatment can prevent recurrence of PMC.Recently,microecologic therapy especially the development of vaccine of clostridium difficile will become new research direction in the treatment for PMC .
出处
《医学综述》
2015年第8期1401-1403,共3页
Medical Recapitulate
关键词
伪膜性肠炎
难辨梭状芽孢杆菌
抗生素
诊断
治疗
Pseudomenbraneouscolitis
Clostridium difficile
Antibiotics
Diagnosis
Treatment
