摘要
目的探讨颅内胶质瘤继发癫痫患者脑电图(EEG)临床特征。方法对2010年4月—2014年6月我院收治的以继发癫痫发作为首发症状的51例胶质瘤的临床资料及24 h动态脑电图(24 h EEG)检查结果进行回顾性分析。结果本组头颅CT和(或)MRI检查示病灶位于额叶12例;颞叶26例,其中位于颞叶新皮层10例,前内侧颞叶7例,后内侧颞叶及颞-枕交界区5例,颞叶内外侧4例;顶叶9例;枕叶4例。24 h EEG检查正常13例,异常38例,其中轻度异常23例,中度异常11例,重度异常4例。术后病理检查示星形细胞瘤19例(Ⅱ级),少突-星形细胞瘤14例(Ⅱ级),神经节胶质细胞瘤9例(Ⅰ级),少突-胶质细胞瘤7例(Ⅱ级),室管膜瘤2例(Ⅱ级)。本组术后平均随访7.4个月。33例术后无明显癫痫发作,18例术后仍有癫痫发作。结论 EEG改变及影像学检查可帮助颅内胶质瘤的诊断与定位,手术是治疗颅内胶质瘤继发癫痫的重要措施。
Objective To study the clinical features of EEG in glioma patients with secondary epilepsy. Methods The clinical data and 24 h Electroencephalogram （24 h EEG） of 51 glioma patients with the first clinical symptom of epilepsy during April 2010 and June 2014 in our hospital were retrospectively analyzed. Results Cranial CT and （ or） MRI examina-tion revealed the lesions in the 51 cases, of which 12 cases were located in the frontal lobe, 26 cases located in the temporal lobe （10 cases in the new temporal lobe cortex, 7 cases in prior to the medial temporal lobe, 5 cases in the medial temporal lobe and the temporal-pillow after border area, 4 cases inside and outside the temporal lobe） , 9 cases located in the parietal lobe, 4 cases located in the occipital lobe. 24 h EEG revealed that 13 cases were normal, and 38 cases were abnormal, of which 23 were mild, 11 were moderate and 4 were serious. Postoperative pathological examination revealed that 19 cases were astrocytoma （ WHO Ⅱ） , 14 cases were oligoastrocytoma （ WHO Ⅱ） , 9 cases （ WHOⅠ） were ganglion glial cell tumor, 7 cases were oligodendroglioma （WHO Ⅱ）, 2 cases were ependymoma （WHO Ⅱ）. The follow-up （mean 7. 4 months）re-vealed that 33 cases had no obvious seizures after operation, while 18 cases still had seizures. Conclusion The change of EEG and imaging can help early diagnosis and positioning of intracerebral gliomas. Surgery is an important approach to treat gliomas epilepsy.
出处
《临床误诊误治》
2015年第5期79-82,共4页
Clinical Misdiagnosis & Mistherapy
关键词
神经胶质瘤
癫痫
脑电图
Glioma
Epilepsy
Electroencephalogram
