摘要
目的：观察地佐辛预防小儿全麻苏醒期躁动的临床效果。方法：选择全麻下行下腹部手术的患儿60例，年龄2--9岁，随机分为地佐辛组和对照组。地佐辛组在手术结束前约30 min静注0．1 mg/kg地佐辛，对照组注入等量生理盐水。记录患儿拔管后0 min、10 min、20 min 及30 min的躁动评分和CHEOPS镇静评分；同时记录手术、麻醉、清醒和拔管时间及术后6 h不良反应发生率。结果：地佐辛组无/轻度躁动发生率明显高于对照组（77%vs 20%）（ P〈0．05），而中、重度躁动评分发生率地佐辛组明显低于对照组（23%vs 80%）（P〈0．05）；地佐辛组各时点CHEOPS镇静评分均明显低于对照组（P〈0．05）。结论：小儿手术结束前约30 min静注0．1 mg/kg地佐辛可获得苏醒期良好的镇静效果，减少躁动发生，且不增加拔管时间和术后6h不良反应发生率。
Objective：To investigate the preventive effect of dezocine on emergence agitation during the recovery of general an-esthesia in children. Methods：Sixty children aged 2 to 9 years old undergoing lower abdominal surgery were assigned randomly into two groups with 30 cases in each. Dezocine group was injected intravenously with dezocine 0. 1 mg/kg 30 min before the end of surgery, while control group was received the same volume of normal saline. The incidence of emergence agitation and CHEOPS scores were e-valuated at the time point of 0 min,10 min,20 min and 30 min after extubation. The time of surgery,anesthesia,recovery and extubation were recorded. Adverse effects in each group were also recorded. Results：The incidence of no or mild emergence agitation was 85% in the dezocine group,which was higher than that in the control group （77% vs20%,P〈0. 05）. While the incidence of moderate and se-vere emergence agitation in the dezocine group was obviously lower than that in the control group （23% vs80%,P〈0. 05）. The scores of CHEOPS at each time point in the dezocine group were significantly lower than those in the control group （P〈0. 05）. There were no significant differences in the time of surgery,anesthesia recovery and extubation and the occurrence of adverse effects between the two groups. Conclusion：Injection of dezocine 0. 1 mg/kg 30 min before the end of operation produces a favorable sedation effect without prolongation of extubation and adverse sides during the emergence from general anesthesia in children.
出处
《川北医学院学报》
CAS
2015年第2期228-230,共3页
Journal of North Sichuan Medical College
关键词
地佐辛
躁动
全身麻醉
小儿
Dezocine
Emergence agitation
General anesthesia
Children
