摘要
目的应用超声二维斑点追踪技术评价肥厚型心肌病（hypertrophic cardiomyopathy，HCM）患者左室各层心肌，包括心内膜下心肌、中层心肌及心外膜下心肌的收缩功能。方法选取HCM患者和正常对照组各32例，分别获取二尖瓣、乳头肌及心尖部水平的左室短轴观，以及心尖四腔、二腔及左室长轴观，应用二维斑点追踪技术测量各组的左室整体径向峰值应变、各层心肌的圆周峰值应变及纵向峰值应变。结果HCM组和对照组中圆周应变和纵向应变的峰值均为心内膜下心肌〉中层心肌〉心外膜下心肌。HCM组的左室整体径向峰值应变明显低于对照组，HCM组心内膜下、中层及心外膜下心肌的纵向峰值应变均低于对照组。而心内膜下心肌的圆周应变，HCM组稍低于对照组，但差异无统计学意义。结论左室各层心肌的应变不同，纵向应变和圆周应变都是由心内膜下到心外膜下呈递减趋势。肥厚型心肌病患者各层心肌纵向应变均减低，而圆周应变主要为心外膜下心肌与中层心肌减低。
Objective To assess the systolic function in left ventricular subendocardial myocardium, midmyocardium and subepicardial myocardium in patients with hypertrophic cardiomyopathy （HCM） by two-dimensional speckle tracking echocardiography. Methods A total of 32 patients with HCM and 32 healthy adults were included in the study. All standard measurements were obtained from the left ventricular short-axis views at the levels of mitral annulus, papillary muscle and apex, and apical four-chamber, two- chamber,and long-axis views. Two-dimensional speckle tracking imaging was employed. The global peak systolic radial strain, peak systolic longitudinal strain and circumferential strain of each layer of the left ventricle were measured. Results In patients with HCM and the control group, the peak systolic longitudinal strain and circumferential strain reduced from subendocardial myocardium to subepicardial myocardium. The global peak systolic radial strain in patients with HCM was significant lower than that in the control group. And in patients with HCM, peak systolic longitudinal strain in subendocardial myocardium, midmyocardium and subepicardial myocardium was significant lower than those in the control group. Conclusions Peak systolic longitudinal strain and circumferential strain are reduced from subendocardial myocardium to subepicardial rnyocardium.Myocardial systolic function is impaired in patients with HCM. In patients with HCM, longitudinal strain of each layer is lower, hut circumferential strain is mainly reduced in midmyocardium and subepicardial myocardium compared with that in the control group.
出处
《中华超声影像学杂志》
CSCD
北大核心
2015年第4期277-281,共5页
Chinese Journal of Ultrasonography
关键词
超声心动描记术
心肌病
肥厚型
心室功能
左
二维斑点追踪显像
Echocardiography
Cardiomyopathy, hypertrophic
Ventricular function, left
Two-dimensional speckle tracking imaging
