摘要
目的：探讨早产儿肺出血的临床特征及危险因素。方法：收集2011年1月～2014年10月博罗县妇幼保健院收治的106例早产合并肺出血患儿的临床资料,分析患儿的原发病因及临床特征;采用Logistic回归方程计算早产儿肺出血的相关危险因素。结果：观察组患儿原发病中非感染性疾病以新生儿窒息（54.72%）最常见,其次是肺透明膜病（41.51%）;感染性疾病以新生儿肺炎为主（47.17%）;患儿均在原发病基础上出现口唇发绀、面部苍白、呼吸困难及吸气三凹征;气管导管中可见红色血性液体;肺部伴有明显湿啰音,心率减慢,部分患儿出现四肢肌张力降低。单因素分析显示：观察组低出生体重、妊娠期高血压疾病（HDCP）、新生儿窒息、肺透明膜病、新生儿寒冷损伤综合征及新生儿肺炎发生率显著高于对照组,两组比较差异有统计学意义（P〈0.05）;多因素分析显示低出生体重、HDCP、新生儿窒息、寒冷损伤综合征及新生儿肺炎是导致早产儿肺出血的危险因素（P〈0.05）。结论：临床上应对早产儿肺出血的危险因素加强监测,以便早期诊断、及时治疗,从而降低早产儿肺出血的发病率和病死率。
Objective： To explore the clinical characteristics and risk factors of pneumorrhagia among premature infants. Meth- ods： The clinical data of 106 preterm infants with pneumorrhagia treated in the hospital from January 2011 to October 2014 were collected, the primary causes and clinical characteristics of the infants were analyzed; Logistic regression equation was used to calculate the related risk factors of pneumorrhagia of premature infants. Results： In observation group, neonatal asphyxia （54. 72% ） was the most common disease among noninfectious diseases, followed by pulmonary hyaline membrane disease （41.51% ） ; neonatal pneumonia （47. 17% ） was the most common disease among infectious diseases ; based on the symptoms of primary diseases, all the infants were found with cyanosis of lips, pale face, dyspnea, and three-concave sign; bloody fluid was found in tracheal catheter; pulmonary moist rales were obvious, heart rate slowed, partial infants were found with decreased muscular tension of arms and legs. Univariate analysis showed that the incidence rates of low birth weight, hypertensive disorder complicating pregnancy （HDCP）, neonatal asphyxia, hyaline membrane disease, neonatal cold injury syn- drome, and neonatal pneumonia in observation group were statistically significantly higher than those in control group （P〈0. 05 ） ; multivari- ate analysis showed that low birth weight, HDCP, neonatal asphyxia, neonatal cold injury syndrome, and neonatal pneumonia were risk fac- tors of pneumorrhagia of premature infants （P〈0. 05 ） . Conclusion： Monitoring of risk factors of pneumorrhagia among premature infants should be strengthened for early diagnosis and timely treatment, then the incidence rate and mortality rate of premature infants with pneumor- rhagia can be reduced.
出处
《中国妇幼保健》
CAS
2015年第15期2371-2373,共3页
Maternal and Child Health Care of China
基金
广东省惠州市科技计划项目〔20110803〕
关键词
早产儿
肺出血
临床特征
危险因素
Premature infant
Pneumorrhagia
Clinical characteristics
Risk factor
