摘要
目的：探讨超声弹性成像应变率比值法在鉴别乳腺肿瘤良恶性的价值。方法通过应用超声弹性成像应变率比值法，回顾分析2011年9月～2014年9月216例在我院检出并经病理证实的268个乳腺肿块，获得乳腺肿块与同深度周围组织的应变率比值，并采用ROC曲线分析鉴别乳腺良恶性的最佳诊断界点。结果恶性肿瘤的应变率比值（SR值）（4．9±2．94）显著大于良性肿瘤（1．80±1．11），差异有统计学意义（t＝2．257，P＝0．000）。超声弹性成像比值法对乳腺病灶的最佳诊断界点3．10，其ROC曲线下面积为0．976，其敏感性、特异性及准确性分别为92．2％、98．5％和97．7％。结论对比乳腺肿块与周围组织的硬度，可以更为准确、客观的判断乳腺肿物的良恶性，为临床诊断乳腺癌提供更有价值的量化指标。
Objective To evaluate the stiffness of breast lesions and explore its diagnostic value in differentiating malignant and benign breast lesions. Methods The ultrasound elastography strain rate（SR） ratio of 268 breast lesions detected and confirmed by pathology from 2011-9 to 2014-9 in our station were retrospective analyzed. .The SR ratio of breast lesions and the same depth of the surrounding tissue were summarized and the best cutoff point of UE strain ratios to differentiate benign and malignant was got by ROC curve analysis. Results The strain ratio value of malignant breast tumors （4.9±2.94） were significantly higher than benign ones （1.80±1.11）. The difference was statistically significant （t=2.257, P=0.000）. 3.10 was the best cutoff point of UE strain ratio for differentiating malignant and benign breast lesions. The AUC, sensitivity, specificity and accuracy were 0.976, 92.2%, 98.5%and 97.7%. Conclusion Comparing the stiffness of breast tumor and surrounding tissues, it is a more accurate, objective judgment to diagnose benign or malignant breast tumor, and a more valuable quantitative index for diagnosing breast tumor.
出处
《影像诊断与介入放射学》
2015年第2期134-137,共4页
Diagnostic Imaging & Interventional Radiology
基金
2014浙江省人口计划生育科研项目(2014KYA266)
关键词
乳腺肿块
超声弹性成像
应变率比值
组织硬度
鉴别诊断
Breast lesions
Ultrasonography elastography （UE）
Strain ratios （SR）
Tissue stiffness
Differential diagnosis
