摘要
目的分析尿胰蛋白酶原-2、C反应蛋白和血清降钙素原在急性胰腺炎继发感染患者诊断中的临床价值。方法将收治的60例急性胰腺炎患者根据症状、体征和实验室检查分为继发感染组32例,未继发感染组28例,动态比较两组患者尿胰蛋白酶原-2、C反应蛋白和血清降钙素原的变化。结果继发感染组血清C反应蛋白在入院后第1、3、5、7天明显高于未继发感染组,差异有统计学意义(P<0.05);继发感染组尿胰蛋白酶原-2阳性率在入院后第5天和第7天明显高于未继发感染组,差异有统计学意义(P<0.05);继发感染组血清降钙素原在入院后第1、3、5、7天明显高于未继发感染组,差异有统计学意义(P<0.05)。结论对急性胰腺炎患者及早进行尿胰蛋白酶原-2、C反应蛋白和血清降钙素原的动态观察,能及时发现患者的病情变化,有助于急性胰腺炎继发感染的早期诊断。
Objective To analyze the clinical value of urine trypsinogen‐2 ,serum C‐reactive protein（CRP） and procalcitonin for the diagnosis of secondary infection in the patients with acute pancreatitis .Methods 60 cases of a‐cute pancreatitis were divided into the secondary infection group（32 cases） and the non‐secondary infection group （28 cases） according to thesymptoms ,signs and laboratory detection results .The changes of urine trypsinogen‐2 ,CRP and serum procalcitonin were dynamically compared between the two groups .Results The serum CRP level on 1 ,3 , 5 ,7 d after admission in the secondary infection group was significantly higher than that in the non-secondary infec‐tion group ,the difference was statistically significant （P〈0 .05）;the positive detection rate of urinary trypsinogen‐2 on 5 ,7 d after admission in the secondary infection group was significantly higher than that in the non-secondary in‐fection group ,the difference was statistically significant （P〈0 .05）;the serum procalcitonin level on 1 ,3 ,5 ,7 d after admission in the secondary infection group was significantly higher than that in the non-secondary infection group with statistically significant difference （P〈0 .05） .Conclusion Conducting the dynamic observation on urinary tryp‐sinogen‐2 ,serum CRP and procalcitonin as soon as possible can timely find the patient′s condition changes and con‐duce to the early diagnosis of acute pancreatitis secondary infection .
出处
《检验医学与临床》
CAS
2015年第9期1245-1247,共3页
Laboratory Medicine and Clinic
