摘要
目的探讨抽动障碍(TD)患儿的临床特征及视频脑电图(VEEG)特征。方法对2011年1月至2013年12月在十堰市太和医院儿童医疗中心就诊的150例TD患儿临床及VEEG资料进行分析。结果 TD患儿视频脑电图异常率为34%(51/150),其中45例表现为枕区基本节律慢化、α波指数减少、不对称、分布异常、调节调幅不良、阵发高幅θ节律等非特异性异常,6例表现为发作间歇期癫痫性放电;短暂性TD、慢性TD、多发性抽动症(TS)患儿脑电图异常率分别为23.1%(18/78)、45.3%(24/53)、47.4%(9/19),差异有统计学意义(x^2=8.667,P<0.05);51例VEEG异常多表现为非特异性异常,其中局限性异常38例(74.5%),广泛性异常13例(25.5%)。结论部分TD患儿VEEG有异常,多为非特异性异常、局限性异常,与病程的长短及严重程度存在一定的对应关系,VEEG可作为临床诊断、评估病变严重程度、指导治疗、判断预后的客观依据之一。
Objective To investigate the clinical and video-electroencephalograph （VEEG） features of children with tic disorder （TD）. Methods Analysis was conducted on the clinical and VEEG data of 150 cases with TD visiting Shiyan Taihe Hospital during the period of January 2011 to December 2013.Results VEEG disorder was found in 51 of 150 （34%）, among whom non-specific disorders were observed in 45 cases, including occipital basic rhythm slowing, abnormal αwave （ rhythm decrease, asymmetry waveform, distribution disorder, and poor adjustment and amplitude modulation） , and paroxysmal high amplitude θ rhythm.Epileptic discharge in intermission was detected in the other 6 cases.The EEG disorder rate was 23.1% （18/78）, 45.3% （24/53）, and 47.4% （9/19） in cases with transient TD, chronic TD and Tourette’s syndrome （TS）, respectively, and the difference was significant （χ^2 =8.667,P〈0.05）.Most of 51 cases with abnormal VEEG showed non-specific abnormality, including 38 cases （ 74.5%） of local abnormality and 13 cases （25.5%） of extensive abnormality.Conclusion Non-specific or local abnormality is found in VEEG of some children with TD, which is correlated with the course and severity of the disease.VEEG can be taken as an objective index for clinical diagnosis, severity rating, treatment planning and prognosis prediction.
出处
《中国妇幼健康研究》
2015年第2期348-350,共3页
Chinese Journal of Woman and Child Health Research
关键词
抽动障碍
儿童
视频脑电图
临床观察
tic disorders （TD）
children
video-electroencephalograph （VEEG）
clinical observation
