摘要
1例61岁男性患者,因结肠息肉入院行腹腔镜下结肠部分切除术,术后给予重组人白介素-2,200万IU静脉滴注,每日一次。用药7d后出现间歇性发热,每于午后及傍晚出现,体温最高达38℃,次日清晨降至正常。综合患者临床表现,考虑与重组人白介素-2有关,建议医师停药。停药后患者体温降至正常后未再出现间歇性发热。此病例提醒广大临床医生对重组人白介素-2引起的药物热应给予足够认识。
A 61 year male patient with polyp of colon was admitted to hospital. After the laparoscopic partial colectomy was administered intravenous infusion of recombinant human interleukin-2（IL-2） 2000,000 IU qd. 7 days after the treatment, the intermittent fever was found. The temperature of the patient rose to about 38℃ every afternoon and gradually fell to normal at the next morning. Recombinant human interleukin-2 was considered the cause according to the clinical feature of the patient. It was discontinued immediately as the pharmacist suggested. And then the patient＇s temperature return to normal and the intermittent fever did not recur until discharged. This case reminds clinician aware of IL-2＇s adverse reaction like drug-fever, thus more attention should be paid to it for medical treatment.
出处
《药品评价》
CAS
2015年第4期43-44,共2页
Drug Evaluation
关键词
重组人白介素-2
不良反应
药物热
Recombinant Human Interleukin-2
Adverse Drug Reactions
Drug-fever
